Nuclear reprogramming of cloned embryos and its implications for therapeutic cloning
Therapeutic cloning, whereby somatic cell nuclear transfer (SCNT) is used to generate
patient-specific embryonic stem cells (ESCs) from blastocysts cloned by nuclear transfer …
patient-specific embryonic stem cells (ESCs) from blastocysts cloned by nuclear transfer …
Paternal contribution: new insights and future challenges
SA Krawetz - Nature Reviews Genetics, 2005 - nature.com
It has been widely held that all that fathers essentially contribute to the next generation is
half their genome. However, recent progress towards understanding biological processes …
half their genome. However, recent progress towards understanding biological processes …
Mitochondrial DNA transmission, replication and inheritance: a journey from the gamete through the embryo and into offspring and embryonic stem cells
JC St. John, J Facucho-Oliveira, Y Jiang… - Human reproduction …, 2010 - academic.oup.com
Abstract BACKGROUND Mitochondrial DNA (mtDNA) encodes key proteins associated with
the process of oxidative phosphorylation. Defects to mtDNA cause severe disease …
the process of oxidative phosphorylation. Defects to mtDNA cause severe disease …
Phenotypic differences in genetically identical organisms: the epigenetic perspective
AHC Wong, II Gottesman… - Human molecular …, 2005 - academic.oup.com
Human monozygotic twins and other genetically identical organisms are almost always
strikingly similar in appearance, yet they are often discordant for important phenotypes …
strikingly similar in appearance, yet they are often discordant for important phenotypes …
Tissue engineering and regenerative medicine: concepts for clinical application
A Atala - Rejuvenation research, 2004 - liebertpub.com
Patients suffering from diseased and injured organs may be treated with transplanted
organs. However, there is a severe shortage of donor organs that is worsening yearly given …
organs. However, there is a severe shortage of donor organs that is worsening yearly given …
Bovine embryo technologies
C Galli, R Duchi, G Crotti, P Turini, N Ponderato… - Theriogenology, 2003 - Elsevier
Embryo technologies are a combination of assisted reproduction, cellular and molecular
biology and genomic techniques. Their classical use in animal breeding has been to …
biology and genomic techniques. Their classical use in animal breeding has been to …
Nuclear transplantation, embryonic stem cells, and the potential for cell therapy
K Hochedlinger, R Jaenisch - New England Journal of Medicine, 2003 - Mass Medical Soc
Nuclear Transplantation, Embryonic Stem Cells, and the Potential for Cell Therapy | New
England Journal of Medicine Skip to main content The New England Journal of Medicine …
England Journal of Medicine Skip to main content The New England Journal of Medicine …
Birth of African Wildcat cloned kittens born from domestic cats
MC Gómez, C Earle Pope, A Giraldo… - Cloning and stem …, 2004 - liebertpub.com
In the present study, we used the African Wildcat (Felis silvestris lybica) as a somatic cell
donor to evaluate the in vivo developmental competence, after transfer into domestic cat …
donor to evaluate the in vivo developmental competence, after transfer into domestic cat …
Epigenetic marks: regulators of livestock phenotypes and conceivable sources of missing variation in livestock improvement programs
EM Ibeagha-Awemu, X Zhao - Frontiers in genetics, 2015 - frontiersin.org
Improvement in animal productivity has been achieved over the years through careful
breeding and selection programs. Today, variations in the genome are gaining increasing …
breeding and selection programs. Today, variations in the genome are gaining increasing …
Therapeutic potential of embryonic stem cells
Nearly 20 years after murine embryonic stem cells (mESC) were isolated, the first report of
the derivation of human embryonic stem cells (hESC) in 1998 spawned the field of hESC …
the derivation of human embryonic stem cells (hESC) in 1998 spawned the field of hESC …