Asymmetric organocatalysis: an enabling technology for medicinal chemistry
B Han, XH He, YQ Liu, G He, C Peng… - Chemical Society Reviews, 2021 - pubs.rsc.org
The efficacy and synthetic versatility of asymmetric organocatalysis have contributed
enormously to the field of organic synthesis since the early 2000s. As asymmetric …
enormously to the field of organic synthesis since the early 2000s. As asymmetric …
A high-stringency blueprint of the human proteome
Abstract The Human Proteome Organization (HUPO) launched the Human Proteome Project
(HPP) in 2010, creating an international framework for global collaboration, data sharing …
(HPP) in 2010, creating an international framework for global collaboration, data sharing …
Towards the overcoming of anticancer drug resistance mediated by p53 mutations
Cancer continues to be a leading threat to human health and life. Resistance to anti-cancer
drugs is a major impediment towards efficacious cancer treatment. p53 mutations play an …
drugs is a major impediment towards efficacious cancer treatment. p53 mutations play an …
Seeing the complete picture: proteins in top-down mass spectrometry
Top-down protein mass spectrometry can provide unique insights into protein sequence and
structure, including precise proteoform identification and study of protein–ligand and protein …
structure, including precise proteoform identification and study of protein–ligand and protein …
Polystyrene microplastics mediate cell cycle arrest, apoptosis, and autophagy in the G2/M phase through ROS in grass carp kidney cells
H Lu, L Hou, Y Zhang, T Guo, Y Wang… - Environmental …, 2024 - Wiley Online Library
Microplastics (MPs) have attracted widespread worldwide attention as a new pollutant.
However, the role of reactive oxygen species (ROS) and cell cycle in nephrotoxicity induced …
However, the role of reactive oxygen species (ROS) and cell cycle in nephrotoxicity induced …
The human melanoma proteome atlas—Complementing the melanoma transcriptome
The MM500 meta‐study aims to establish a knowledge basis of the tumor proteome to serve
as a complement to genome and transcriptome studies. Somatic mutations and their effect …
as a complement to genome and transcriptome studies. Somatic mutations and their effect …
Clinical challenges of tissue preparation for spatial transcriptome
Spatial transcriptomics is considered as an important part of spatiotemporal molecular
images to bridge molecular information with clinical images. Of those potentials and …
images to bridge molecular information with clinical images. Of those potentials and …
The human melanoma proteome atlas—Defining the molecular pathology
The MM500 study is an initiative to map the protein levels in malignant melanoma tumor
samples, focused on in‐depth histopathology coupled to proteome characterization. The …
samples, focused on in‐depth histopathology coupled to proteome characterization. The …
[HTML][HTML] Towards precision dermatology: emerging role of proteomic analysis of the skin
Background: The skin is the largest organ in the human body and serves as a multilayered
protective shield from the environment as well as a sensor and thermal regulator. However …
protective shield from the environment as well as a sensor and thermal regulator. However …
[HTML][HTML] The role of neutrophil extracellular traps in cancer metastasis
W Wang, J Zhang, N Zheng, L Li, X Wang… - Clinical and …, 2020 - ncbi.nlm.nih.gov
Extracellular traps are web-like structures and consist of chromatin DNA filaments, histones,
and granule proteins. These are released together with inflammatory mediators and …
and granule proteins. These are released together with inflammatory mediators and …