Common variable immunodeficiency (CVID) is a heterogeneous disorder characterized by
hypogammaglobulinemia and increased susceptibility to recurrent bacterial infections. It is …

Starting about 60 years ago, a number of reports appeared that outlined the severe clinical
course of a few adult subjects with profound hypogammaglobinemia. Puzzled by the lack of …

Chronic granulomatous disease (CGD) is an innate immunodeficiency with a genetic defect
of the nicotinamide adenosine dinucleotide phosphate, reduced, oxidase components. This …

WHIM syndrome is a rare combined primary immunodeficiency disease named by acronym
for the diagnostic tetrad of warts, hypogammaglobulinemia, infections, and myelokathexis …

Common variable immunodeficiency (CVID) is the most common symptomatic primary
antibody immunodeficiency, characterized by reduced serum levels of IgG, IgA, and/or IgM …

Mucosal antibodies maintain gut homeostasis by promoting spatial segregation between
host tissues and luminal microbes. Whether and how mucosal antibody responses influence …

Common variable immunodeficiency (CVID) is increasingly recognized for its association
with autoimmune and inflammatory complications. Despite recent advances in …

OBJECTIVES: Common variable immunodeficiency (CVID) is associated with a spectrum of
autoimmune complications. We studied the prevalence of gastrointestinal (GI) …

A broad spectrum of autoimmunity is now well described in patients with primary
immunodeficiencies (PIDs). Management of autoimmune disease in the background of PID …

Common variable immunodeficiency (CVID) is the most frequent primary immunodeficiency
(PID) in adulthood and is characterized by severe reduction of immunoglobulin serum levels …