Vitamin E: Emerging aspects and new directions

F Galli, A Azzi, M Birringer, JM Cook-Mills… - Free Radical Biology …, 2017 - Elsevier
The discovery of vitamin E will have its 100th anniversary in 2022, but we still have more
questions than answers regarding the biological functions and the essentiality of vitamin E …

Many tocopherols, one vitamin E

A Azzi - Molecular aspects of medicine, 2018 - Elsevier
Four tocopherols are available in nature and are absorbed with the diet, but only one RRR-α-
tocopherol satisfies the criteria of being a vitamin. The biological activity of the different …

Antioxidants as therapeutic agents for liver disease

AK Singal, SC Jampana, SA Weinman - Liver International, 2011 - Wiley Online Library
Oxidative stress is commonly associated with a number of liver diseases and is thought to
play a role in the pathogenesis of chronic hepatitis C, alcoholic liver disease, non‐alcoholic …

Redox state and methods to evaluate oxidative stress in liver damage: From bench to bedside

J Arauz, E Ramos-Tovar, P Muriel - Annals of Hepatology, 2016 - medigraphic.com
Oxidative stress is importantly involved in the pathophysiology of various liver diseases. The
redox state participates on the course of the inflammatory, metabolic and proliferative liver …

Nutrition assessment and management in advanced liver disease

TM Johnson, EB Overgard, AE Cohen… - Nutrition in Clinical …, 2013 - Wiley Online Library
Malnutrition commonly complicates the course of patients with cirrhosis and has a
multifactorial etiology. Despite the important role that nutrition plays in the prognosis of those …

The role of nutrients in the development, progression, and treatment of nonalcoholic fatty liver disease

M Mouzaki, JP Allard - Journal of clinical gastroenterology, 2012 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is the most common cause of liver disease in
adults and children and is currently the third most common indication for liver transplantation …

[HTML][HTML] Diagnosis and treatment of nutritional deficiencies in alcoholic liver disease: Overview of available evidence and open issues

RE Rossi, D Conte, S Massironi - Digestive and Liver Disease, 2015 - Elsevier
Malnutrition is common in alcoholic liver disease and is associated with high rates of
complications and mortality. In this article, the current literature was reviewed to highlight the …

Association between serum and dietary antioxidant micronutrients and advanced liver fibrosis in non-alcoholic fatty liver disease: an observational study

JM Coelho, K Cansanção, R de Mello Perez, NC Leite… - PeerJ, 2020 - peerj.com
Background Despite clinical trials with antioxidant supplementation, few studies have been
conducted to evaluate the nutritional status of antioxidant vitamins and minerals, and none …

Nonalcoholic fatty liver disease impairs the cytochrome P-450-dependent metabolism of α-tocopherol (vitamin E)

D Bartolini, P Torquato, C Barola, A Russo… - The Journal of …, 2017 - Elsevier
This study aims to investigate in in vivo and in vitro models of nonalcoholic fatty liver disease
(NAFLD) the enzymatic metabolism of α-tocopherol (vitamin E) and its relationship to vitamin …

Increased plasma levels of the lipoperoxyl radical-derived vitamin E metabolite α-tocopheryl quinone are an early indicator of lipotoxicity in fatty liver subjects

P Torquato, D Bartolini, D Giusepponi, M Piroddi… - Free Radical Biology …, 2019 - Elsevier
Lipid peroxidation is one of the earliest pathogenic events of non-alcoholic fatty liver disease
(NAFLD). In this context, an increased oxidation of the lipoperoxyl radical scavenger α …