Placental insufficiency and adipose tissue dysregulation are postulated to play key roles in
the pathophysiology of both pre-eclampsia (PE) and gestational diabetes mellitus (GDM). A …

Pre-eclampsia (PE) continues to be a leading cause of maternal and fetal mortality and
morbidity. While substantial progress has been made in understanding the …

Preeclampsia is a pregnancy-related disorder characterized by hypertension and could lead
to maternal and fetal morbidity and mortality. Although the causative factors and …

Objective: To evaluate the placental and decidual gene expression and maternal and
umbilical serum concentrations of tumor necrosis factor alpha, interleukin 6 (IL-6), IL-8, IL …

Context Extensive studies have provided considerable evidence suggesting the role of
inflammation in the development of female reproductive diseases. However, causality has …

Preeclampsia is caused by placental impairment with increased expression of sFlt-1
(soluble fms-like tyrosine kinase 1) and decreased PlGF (placental growth factor); it has …

The endothelium, which constitutes the inner layer of blood vessels and lymphatic
structures, plays an important role in various physiological functions. Alterations in structure …

Preeclampsia (PE) is a multisystemic disorder of pregnancy that not only causes perinatal
mortality and morbidity but also has a long-term toll on the maternal and fetal cardiovascular …

Preeclampsia is a pregnancy-specific syndrome characterized by a sudden increase in
blood pressure accompanied by proteinuria and/or maternal multi-system damage …

Endoglin, alias CD105, is a human membrane glycoprotein highly expressed in vascular
endothelial cells. It is involved in angiogenesis and angiogenesis-related diseases …