Half a century of amyloids: past, present and future

PC Ke, R Zhou, LC Serpell, R Riek… - Chemical Society …, 2020 - pubs.rsc.org
Amyloid diseases are global epidemics with profound health, social and economic
implications and yet remain without a cure. This dire situation calls for research into the …

Secretion systems in Gram-negative bacteria: structural and mechanistic insights

TRD Costa, C Felisberto-Rodrigues, A Meir… - Nature Reviews …, 2015 - nature.com
Bacteria have evolved a remarkable array of sophisticated nanomachines to export various
virulence factors across the bacterial cell envelope. In recent years, considerable progress …

Giving structure to the biofilm matrix: an overview of individual strategies and emerging common themes

L Hobley, C Harkins, CE MacPhee… - FEMS microbiology …, 2015 - academic.oup.com
Biofilms are communities of microbial cells that underpin diverse processes including
sewage bioremediation, plant growth promotion, chronic infections and industrial biofouling …

Curli biogenesis and function

MM Barnhart, MR Chapman - Annu. Rev. Microbiol., 2006 - annualreviews.org
Curli are the major proteinaceous component of a complex extracellular matrix produced by
many Enterobacteriaceae. Curli were first discovered in the late 1980s on Escherichia coli …

A dual-constriction biological nanopore resolves homonucleotide sequences with high fidelity

SE Van der Verren, N Van Gerven, W Jonckheere… - Nature …, 2020 - nature.com
Single-molecule long-read DNA sequencing with biological nanopores is fast and high-
throughput but suffers reduced accuracy in homonucleotide stretches. We now combine the …

Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG

P Goyal, PV Krasteva, N Van Gerven, F Gubellini… - Nature, 2014 - nature.com
Curli are functional amyloid fibres that constitute the major protein component of the
extracellular matrix in pellicle biofilms formed by Bacteroidetes and Proteobacteria …

Biofilm formation by enteric pathogens and its role in plant colonization and persistence

S Yaron, U Römling - Microbial biotechnology, 2014 - Wiley Online Library
The significant increase in foodborne outbreaks caused by contaminated fresh produce,
such as alfalfa sprouts, lettuce, melons, tomatoes and spinach, during the last 30 years …

Simulation studies of amyloidogenic polypeptides and their aggregates

IM Ilie, A Caflisch - Chemical reviews, 2019 - ACS Publications
Amyloids, fibrillar assembly of (poly) peptide chains, are associated with neurodegenerative
illnesses such as Alzheimer's and Parkinson's diseases, for which there are no cures. The …

Amyloid fibrils: abnormal protein assembly

RN Rambaran, LC Serpell - Prion, 2008 - Taylor & Francis
Amyloid refers to the abnormal fibrous, extracellular, proteinaceous deposits found in organs
and tissues. Amyloid is insoluble and is structurally dominated by β‑sheet structure. Unlike …

Amyloid structures as biofilm matrix scaffolds

A Taglialegna, I Lasa, J Valle - Journal of bacteriology, 2016 - Am Soc Microbiol
Recent insights into bacterial biofilm matrix structures have induced a paradigm shift toward
the recognition of amyloid fibers as common building block structures that confer stability to …