Therapeutic manipulation of glucocorticoid metabolism in cardiovascular disease

PWF Hadoke, J Iqbal, BR Walker - British journal of …, 2009 - Wiley Online Library
The therapeutic potential for manipulation of glucocorticoid metabolism in cardiovascular
disease was revolutionized by the recognition that access of glucocorticoids to their …

Worldwide allele frequencies of the human apolipoprotein E gene: climate, local adaptations, and evolutionary history

DTA Eisenberg, CW Kuzawa… - American journal of …, 2010 - Wiley Online Library
The ϵ4 allele of the apolipoprotein E (APOE) gene is associated with increased cholesterol
levels and heart disease. Population allele frequencies of APOE have previously been …

A multi-center, open label, crossover designed prospective study evaluating the effects of lipid lowering treatment on steroid synthesis in patients with Type 2 diabetes …

M Kanat, E Serin, A Tunçkale, O Yildiz, S Sahin… - Journal of …, 2009 - Springer
Objective: It has been suggested that lipid-lowering treatment with the use of statins
adversely affects the steroid hormones. However, the safety of lipid lowering treatment …

[HTML][HTML] Isolation during the prepubertal period associated with chronic access to palatable diets: effects on plasma lipid profile and liver oxidative stress

DM Arcego, R Krolow, C Lampert, C Noschang… - Physiology & …, 2014 - Elsevier
Pre-puberty is a critical period for the final maturation of the neural circuits that control
energy homeostasis, as external stimuli such as exposure to diets and stress may influence …

Association of paraoxonase gene polymorphisms with sperm parameters

LA Lazaros, NV Xita, EG Hatzi, AI Kaponis… - Journal of …, 2011 - Wiley Online Library
Paraoxonase (PON) is a high‐density lipoprotein–associated enzyme that prevents low‐
density lipoprotein oxidation. PON proteins, localized in the seminiferous tubules and in …

Dietary cholesterol and oxidised cholesterol: effects on sperm characteristics, antioxidant status and hormonal profile in rats

A Khorrami, S Ghanbarzadeh, M Ziaee, S Arami… - Andrologia, 2015 - Wiley Online Library
Present study was designed to compare the potential effects of high serum levels of LDL and
oxidised LDL (Ox LDL) on spermatogenesis parameters in male Wistar rats. Animals were …

Partial filling affinity capillary electrophoresis with cationic poly (vinylpyrrolidone)-based copolymer coatings for studies on human lipoprotein–steroid interactions

AJ Wang, K Vainikka, J Witos, L D'Ulivo, G Cilpa… - Analytical …, 2010 - Elsevier
Human plasma lipoproteins have strong hydrophobic interactions with steroids and their
fatty acyl derivatives such as estradiol fatty acyl esters. In this work, affinity capillary …

Mechanistic profiling of the cAMP-dependent steroidogenic pathway in the H295R endocrine disrupter screening system: new endpoints for toxicity testing

C Vanparys, TLM Hectors, R Blust, W De Coen - Toxicology letters, 2012 - Elsevier
The need for implementation of effects on steroid synthesis and hormone processing in
screening batteries of endocrine disruptive compounds is widely acknowledged. In this …

Oxidative stress and phenotype frequencies of paraoxonase‐1 in teratozoospermia

OF Ozer, H Akbulut, EM Guler, HG Caglar… - Andrologia, 2019 - Wiley Online Library
Oxidative stress causes infertility in men by affecting especially sperm morphology. The aim
of the study was to examine the frequencies of paraoxonase‐1 (PON1) phenotypes and the …

Phytosterol additive boosts adrenal response to ACTH in male Japanese quail (Coturnix coturnix japonica)

F Liu, J Chen, F Shi, T Wang, G Watanabe, K Taya - Endocrine, 2012 - Springer
To investigate the adrenal effect of a phytosterol (PS) additive, 80 male Japanese quail were
divided into four sub-groups and fed 0, 40, 400, and 4,000 ppm of PS, respectively, for 21 …