The recruitment of immune cells is crucial for the development of inflammatory processes.
The classical recruitment cascade of neutrophils into inflamed tissues is well understood …

The chemokine CXCL1/MGSA plays a pivotal role in the host immune response by recruiting
and activating neutrophils for microbial killing at the tissue site. CXCL1 exists reversibly as …

Neutrophil recruitment is a coordinated process that is altered at multiple stages during
sepsis, culminating in defective innate immunity and increased risk of infection in these …

Chemokines exert their function by binding the GPCR class of receptors on leukocytes and
cell surface GAGs in target tissues. Most chemokines reversibly exist as monomers and …

Current research on new therapeutic strategies for sepsis uses different animal models,
such as the lipopolysaccharide-induced endotoxemia model and the cecal ligation and …

Sepsis-associated mortality is highly related to the development of the multi-organ
dysfunction syndrome (MODS). MODS represents a virulent and often incremental assault …

Chemokine CXCL8 plays a pivotal role in host immune response by recruiting neutrophils to
the infection site. CXCL8 exists as monomers and dimers, and mediates recruitment by …

Preterm birth (PTB) complicates more than 12% of all deliveries. Despite significant
research, the aetiology of most cases of PTB remains elusive. Two major antecedents of …

Abstract Syndecan‐1 (SDC 1), with a variable ectodomain carrying heparan sulphate (HS)
chains between different Syndecans, participates in many steps of inflammatory responses …

Ineffectiveness of antibiotics in treating neonatal Escherichia coli K1 meningitis and the
emergence of antibiotic-resistant strains evidently warrants new prevention strategies. We …