Wilson disease: an overview and approach to management

C Mulligan, JM Bronstein - Neurologic clinics, 2020 - neurologic.theclinics.com
Wilson disease is one of the few movement disorders in which there are therapies that
modify disease progression. This disease is caused by copper overload primarily in the liver …

Wilson's disease: update on pathogenesis, biomarkers and treatments

S Shribman, A Poujois, O Bandmann… - Journal of Neurology …, 2021 - jnnp.bmj.com
Wilson's disease is an autosomal–recessive disorder of copper metabolism caused by
mutations in ATP7B and associated with neurological, psychiatric, ophthalmological and …

Wilson's disease: an update on the diagnostic workup and management

B Kasztelan-Szczerbinska, H Cichoz-Lach - Journal of clinical medicine, 2021 - mdpi.com
Wilson's disease (WD) is a rare autosomal recessive disorder of hepatocellular copper
deposition. The diagnostic approach to patients with WD may be challenging and is based …

The implications of zinc therapy in combating the COVID-19 global pandemic

N Samad, TE Sodunke, AR Abubakar… - Journal of …, 2021 - Taylor & Francis
The global pandemic from COVID-19 infection has generated significant public health
concerns, both health-wise and economically. There is no specific pharmacological antiviral …

Performance of active learning models for screening prioritization in systematic reviews: a simulation study into the Average Time to Discover relevant records

G Ferdinands, R Schram, J de Bruin, A Bagheri… - Systematic …, 2023 - Springer
Background Conducting a systematic review demands a significant amount of effort in
screening titles and abstracts. To accelerate this process, various tools that utilize active …

Investigation and management of Wilson's disease: a practical guide from the British Association for the Study of the Liver

S Shribman, T Marjot, A Sharif… - The Lancet …, 2022 - thelancet.com
Wilson's disease is an autosomal-recessive disorder of copper metabolism with hepatic,
neurological, psychiatric, ophthalmological, haematological, renal, and rheumatological …

The role of zinc in the treatment of Wilson's disease

A Avan, A Członkowska, S Gaskin, A Granzotto… - International journal of …, 2022 - mdpi.com
Wilson's disease (WD) is a hereditary disorder of copper metabolism, producing abnormally
high levels of non-ceruloplasmin-bound copper, the determinant of the pathogenic process …

[HTML][HTML] Zinc toxicity

UM Agnew, TL Slesinger - 2020 - europepmc.org
Objectives: Review the typical presentation of a patient with zinc toxicity. Describe the
management considerations for patients with zinc toxicity. Outline the treatment options for …

Copper and iron ions accelerate the prion-like propagation of α-synuclein: a vicious cycle in Parkinson's disease

Y Li, C Yang, S Wang, D Yang, Y Zhang, L Xu… - International journal of …, 2020 - Elsevier
Protein fibrils drive the onset and progression of many diseases in a prion-like manner, ie
they transcellular propagate through the extracellular space to health cells to initiate toxic …

[HTML][HTML] Wilson's disease: Revisiting an old friend

A Lucena-Valera, D Perez-Palacios… - World journal of …, 2021 - ncbi.nlm.nih.gov
Wilson's disease (WD) is a rare condition caused by copper accumulation primarily in the
liver and secondly in other organs, such as the central nervous system. It is a hereditary …