Alzheimer's disease
JAS Lopez, HM González, GC Léger - Handbook of clinical neurology, 2019 - Elsevier
Alzheimer's disease (AD) dementia refers to a particular onset and course of cognitive and
functional decline associated with age together with a particular neuropathology. It was first …
functional decline associated with age together with a particular neuropathology. It was first …
The neuropathological diagnosis of Alzheimer's disease
MA DeTure, DW Dickson - Molecular neurodegeneration, 2019 - Springer
Alzheimer's disease is a progressive neurodegenerative disease most often associated with
memory deficits and cognitive decline, although less common clinical presentations are …
memory deficits and cognitive decline, although less common clinical presentations are …
Cognitive training for people with mild to moderate dementia
Background Cognitive impairment, a defining feature of dementia, plays an important role in
the compromised functional independence that characterises the condition. Cognitive …
the compromised functional independence that characterises the condition. Cognitive …
Diagnosis of Alzheimer's disease utilizing amyloid and tau as fluid biomarkers
Current technological advancements in clinical and research settings have permitted a more
intensive and comprehensive understanding of Alzheimer's disease (AD). This development …
intensive and comprehensive understanding of Alzheimer's disease (AD). This development …
Optogenetic gamma stimulation rescues memory impairments in an Alzheimer's disease mouse model
G Etter, S van der Veldt, F Manseau… - Nature …, 2019 - nature.com
Abstract Slow gamma oscillations (30–60 Hz) correlate with retrieval of spatial memory.
Altered slow gamma oscillations have been observed in Alzheimer's disease. Here, we use …
Altered slow gamma oscillations have been observed in Alzheimer's disease. Here, we use …
APOE4 is associated with cognitive and pathological heterogeneity in patients with Alzheimer's disease: a systematic review
S Emrani, HA Arain, C DeMarshall, T Nuriel - Alzheimer's research & …, 2020 - Springer
Possession of the ε4 allele of apolipoprotein E (APOE) is the primary genetic risk factor for
the sporadic form of Alzheimer's disease (AD). While researchers have extensively …
the sporadic form of Alzheimer's disease (AD). While researchers have extensively …
Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory decline and subsequent loss of broader cognitive functions. Memory decline in the …
memory decline and subsequent loss of broader cognitive functions. Memory decline in the …
The aging navigational system
The discovery of neuronal systems dedicated to computing spatial information, composed of
functionally distinct cell types such as place and grid cells, combined with an extensive body …
functionally distinct cell types such as place and grid cells, combined with an extensive body …
Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models
The goal of this review is to discuss how behavioral tests in mice relate to the pathological
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …
and neuropsychological features seen in human Alzheimer's disease (AD), and present a …
Epidemiology of Alzheimer disease
The global prevalence of dementia has been estimated to be as high as 24 million, and is
predicted to double every 20 years until at least 2040. As the population worldwide …
predicted to double every 20 years until at least 2040. As the population worldwide …