Detailed metabolic profiling in large-scale epidemiologic studies has uncovered novel
biomarkers for cardiometabolic diseases and clarified the molecular associations of …

Metabolomics is becoming common in epidemiology due to recent developments in
quantitative profiling technologies and appealing results from their applications for …

The Metabolic Syndrome in Men (METSIM) study is a population-based study including
10,197 Finnish men examined in 2005–2010. The aim of the study is to investigate …

Background—Long-term physical inactivity seems to cause many health problems. We
studied whether persistent physical activity compared with inactivity has a global effect on …

Insulin secretion is critical for glucose homeostasis, and increased levels of the precursor
proinsulin relative to insulin indicate pancreatic islet beta-cell stress and insufficient insulin …

We investigated the association of the levels of ketone bodies (KBs) with hyperglycemia and
with 62 genetic risk variants regulating glucose levels or type 2 diabetes in the population …

Background: The causal role of circulating sex hormone-binding globulin (SHBG) for type 2
diabetes is controversial. Information on the relations between SHBG and new biomarkers of …

Objective—There is some evidence that people born with high birth weight may be at
increased risk of cardiovascular disease in adulthood. Details of the underlying mechanisms …

Genetic and environmental factors as well as their interactions contribute to the
pathogenesis of type 2 diabetes. Linkage analysis, candidate gene approaches, genome …

Metabolic syndrome (MetS) is a cluster of metabolic traits associated with an increased risk
of cardiovascular disease and type 2 diabetes mellitus. Central obesity and insulin …