Effects of air pollution on the nervous system and its possible role in neurodevelopmental and neurodegenerative disorders
LG Costa, TB Cole, K Dao, YC Chang, J Coburn… - Pharmacology & …, 2020 - Elsevier
Recent extensive evidence indicates that air pollution, in addition to causing respiratory and
cardiovascular diseases, may also negatively affect the brain and contribute to central …
cardiovascular diseases, may also negatively affect the brain and contribute to central …
[HTML][HTML] PV interneurons: critical regulators of E/I balance for prefrontal cortex-dependent behavior and psychiatric disorders
BR Ferguson, WJ Gao - Frontiers in neural circuits, 2018 - frontiersin.org
Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple
complex behaviors, including working memory, cognitive flexibility, attention, social …
complex behaviors, including working memory, cognitive flexibility, attention, social …
Influence of glutamate and GABA transport on brain excitatory/inhibitory balance
SMS Sears, SJ Hewett - Experimental Biology and Medicine, 2021 - journals.sagepub.com
An optimally functional brain requires both excitatory and inhibitory inputs that are regulated
and balanced. A perturbation in the excitatory/inhibitory balance—as is the case in some …
and balanced. A perturbation in the excitatory/inhibitory balance—as is the case in some …
[HTML][HTML] Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study
AL Danforth, CS Grob, C Struble, AA Feduccia… - …, 2018 - Springer
Objectives To explore feasibility and safety of MDMA-assisted psychotherapy for reduction of
social fear and avoidance that are common in the autistic population. Methods Autistic adults …
social fear and avoidance that are common in the autistic population. Methods Autistic adults …
Common mechanisms of excitatory and inhibitory imbalance in schizophrenia and autism spectrum disorders
R Gao, P Penzes - Current molecular medicine, 2015 - ingentaconnect.com
Autism Spectrum Disorders (ASD) and Schizophrenia (SCZ) are cognitive disorders with
complex genetic architectures but overlapping behavioral phenotypes, which suggests …
complex genetic architectures but overlapping behavioral phenotypes, which suggests …
Influence of maternal thyroid hormones during gestation on fetal brain development
Thyroid hormones (THs) play an obligatory role in many fundamental processes underlying
brain development and maturation. The developing embryo/fetus is dependent on maternal …
brain development and maturation. The developing embryo/fetus is dependent on maternal …
[HTML][HTML] Glutamate and GABA in autism spectrum disorder—a translational magnetic resonance spectroscopy study in man and rodent models
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental syndrome with a high
human and economic burden. The pathophysiology of ASD is largely unclear, thus …
human and economic burden. The pathophysiology of ASD is largely unclear, thus …
[HTML][HTML] Current enlightenment about etiology and pharmacological treatment of autism spectrum disorder
Autistic Spectrum Disorder (ASD) is a complex neurodevelopmental brain disorder
characterized by two core behavioral symptoms, namely impairments in social …
characterized by two core behavioral symptoms, namely impairments in social …
[HTML][HTML] GABAergic dysfunction, neural network hyperactivity and memory impairments in human aging and Alzheimer's disease
J Jiménez-Balado, TS Eich - Seminars in cell & developmental biology, 2021 - Elsevier
In this review, we focus on the potential role of the γ-aminobutyric acidergic (GABAergic)
system in age-related episodic memory impairments in humans, with a particular focus on …
system in age-related episodic memory impairments in humans, with a particular focus on …
Increased functional connectivity between subcortical and cortical resting-state networks in autism spectrum disorder
Importance Individuals with autism spectrum disorder (ASD) exhibit severe difficulties in
social interaction, motor coordination, behavioral flexibility, and atypical sensory processing …
social interaction, motor coordination, behavioral flexibility, and atypical sensory processing …