The origin and pathogenesis of endometriosis

Y Wang, K Nicholes, IM Shih - Annual Review of Pathology …, 2020 - annualreviews.org
Recent molecular genetic findings on endometriosis and normal endometrium suggest a
modified model in which circulating epithelial progenitor or stem cells intended to …

Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology

SW Guo - Human Reproduction Update, 2020 - academic.oup.com
BACKGROUND Endometriosis is a benign gynaecological disease. Thus, it came as a
complete surprise when it was reported recently that the majority of deep endometriosis …

Fallopian tube epithelial cells express androgen receptor and have a distinct hormonal responsiveness when compared with endometrial epithelium

A Maclean, E Bunni, S Makrydima… - Human …, 2020 - academic.oup.com
STUDY QUESTION How does steroid receptor expression, proliferative activity and
hormone responsiveness of the fallopian tube (FT) epithelium compare to that of the …

Pathology and pathogenesis of adenomyosis

MF Antero, A Ayhan, J Segars… - Seminars in reproductive …, 2020 - thieme-connect.com
Adenomyosis represents a unique pathophysiological condition in which normal-appearing
endometrial mucosa resides within myometrium and is thus protected from menstrual …

[HTML][HTML] Molecular basis of endometriosis and endometrial cancer: Current knowledge and future perspectives

M Terzic, G Aimagambetova, J Kunz… - International journal of …, 2021 - mdpi.com
The human endometrium is a unique tissue undergoing important changes through the
menstrual cycle. Under the exposure of different risk factors in a woman's lifetime, normal …

[HTML][HTML] Endometrial stem cell markers: current concepts and unresolved questions

N Tempest, A Maclean, DK Hapangama - International journal of …, 2018 - mdpi.com
The human endometrium is a highly regenerative organ undergoing over 400 cycles of
shedding and regeneration over a woman's lifetime. Menstrual shedding and the …

[HTML][HTML] Endometrial stem/progenitor cells–their role in endometrial repair and regeneration

FL Cousins, CE Filby, CE Gargett - Frontiers in Reproductive Health, 2022 - frontiersin.org
The human endometrium is a remarkable tissue, undergoing approximately 450 cycles of
proliferation, differentiation, shedding (menstruation), repair and regeneration over a …

[HTML][HTML] Emerging drug targets for endometriosis

MM Dolmans, J Donnez - Biomolecules, 2022 - mdpi.com
Endometriosis is a chronic inflammatory disease causing distressing symptoms and
requiring a life-long management strategy. The objective of this review is to evaluate …

Pathology of endometrioid and clear cell carcinoma of the ovary

O Fadare, V Parkash - Surgical pathology clinics, 2019 - surgpath.theclinics.com
This review is an appraisal of the current state of knowledge of 2 enigmatic histotypes of
ovarian carcinoma: endometrioid and clear cell carcinoma. Both show an association …

[HTML][HTML] A revised stem cell theory for the pathogenesis of endometriosis

T Maruyama - Journal of Personalized Medicine, 2022 - mdpi.com
During the past decade, a stem cell-based hypothesis has emerged (among many others) to
explain the pathogenesis of endometriosis. The initial hypothesis proposed that …