Since its discovery in 2006, the DNA origami technique has revolutionized bottom-up
nanofabrication. This technique is simple yet versatile and enables the fabrication of …

DNA origami technology enables the precise assembly of well-defined two-dimensional and
three-dimensional nanostructures with DNA, an inherently biocompatible material. Given …

Abstract mRNA delivery has shown high application value in the treatment of various
diseases, but its effective delivery is still a major challenge at present. Herein, we propose a …

Breakthroughs in immune checkpoint inhibitor (ICI) therapy have revolutionized clinical
tumor therapy. Immunohistochemistry (IHC) analysis of PD-L1 in tumor tissue has been used …

The ability to apply and measure high forces (> 10 pN) on the nanometer scale is critical to
the development of nanomedicine, molecular robotics, and the understanding of biological …

Two-dimensional (2D) DNA origami is widely used for applications ranging from excitonics
to single-molecule biophysics. Conventional, single-layer 2D DNA origami exhibits flexibility …

The structural stability of DNA origami nanostructures in various chemical environments is
an important factor in numerous applications, ranging from biomedicine and biophysics to …

The stability of DNA origami nanostructures in aqueous media is closely tied to the presence
of cations that screen electrostatic inter‐helix repulsion. Here, the thermal melting behavior …

Atomic force microscopy (AFM) is a powerful technique for imaging molecules,
macromolecular complexes, and nanoparticles with nanometer resolution. However, AFM …

DNA origami structures provide flexible scaffolds for the organization of single biomolecules
with nanometer precision. While they find increasing use for a variety of biological …