Gram-negative bacteremia is a devastating public health threat, with high mortality in
vulnerable populations and significant costs to the global economy. Concerningly, rates of …

Klebsiella pneumoniae is a Gram-negative pathogen responsible for a wide range of
infections, including pneumonia and bacteremia, and is rapidly acquiring antibiotic …

During infection, the host sequesters essential nutrients, such as zinc, to combat invading
microbes. Despite the ability of the immune effector protein calprotectin to bind zinc with …

Increasing occurrence of multidrug-resistant (MDR) and hypervirulent (hv) Klebsiella
pneumoniae (MDR-hvKp) convergent clones is being observed. Those strains have the …

Resources available in the human nasal cavity are limited. Therefore, to successfully
colonize the nasal cavity, bacteria must compete for scarce nutrients. Competition may occur …

Siderophores are small molecular iron chelators that are produced by microbes and whose
most notable function is to sequester iron from the host and provide this essential metal …

Fibrosis is a significant complication of intestinal disorders associated with microbial
dysbiosis and pathobiont expansion, notably Crohn's disease (CD). Mechanisms that favor …

Klebsiella pneumoniae, a member of the autochthonous human gut microbiota, utilizes a
variety of virulence factors for survival and pathogenesis. Consequently, it is responsible for …

Flavobacteriaceae spp. are key players in global biogeochemical cycling and are known for
their versatile carbohydrate and peptide catabolism. However, it is currently unknown …

Achromobacter spp. are opportunistic pathogens of environmental origin increasingly
isolated in patients with underlying conditions like cystic fibrosis (CF). Despite recent …