Micro‐and nanotechnologies have emerged as potentially effective fabrication tools for
addressing the challenges faced in tissue engineering and drug delivery. The ability to …

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia treatable with
antiarrhythmic drugs; however, patient responses remain highly variable. Human induced …

It is becoming increasingly evident that cell biology research can be considerably advanced
through the use of bioengineered tools enabled by nanoscale technologies. Recent …

Direct-write patterning of multiple proteins on surfaces is of tremendous interest for a myriad
of applications. Precise arrangement of different proteins at increasingly smaller dimensions …

Background Cells explore the surfaces of materials through membrane-bound receptors,
such as the integrins, and use them to interact with extracellular matrix molecules adsorbed …

Engineering well-defined scale-spanning structures through transfer of diverse
biomolecules and materials to a surface is of tremendous interest in life sciences research …

Cell adhesion is an important process in several biological phenomena. To investigate the
formation and organization of focal adhesions, we developed a patterning approach based …

Cell adhesion to the extracellular matrix is deregulated in metastasis. However, traditional
surfaces used to study cell adhesion do not faithfully mimic the in vivo microenvironment …

Haptotaxis is critical to cell guidance and development and has been studied in vitro using
either gradients or stripe assays that present a binary choice between full and zero coverage …

Many studies have demonstrated that microscale changes to surface chemistry and
topography affect cell adhesion, proliferation, differentiation, and gene expression. More …