New genes as drivers of phenotypic evolution

S Chen, BH Krinsky, M Long - Nature Reviews Genetics, 2013 - nature.com
During the course of evolution, genomes acquire novel genetic elements as sources of
functional and phenotypic diversity, including new genes that originated in recent evolution …

Sex-specific genetic architecture of human disease

C Ober, DA Loisel, Y Gilad - Nature Reviews Genetics, 2008 - nature.com
Sexual dimorphism in anatomical, physiological and behavioural traits are characteristics of
many vertebrate species. In humans, sexual dimorphism is also observed in the prevalence …

CeNDR, the Caenorhabditis elegans natural diversity resource

DE Cook, S Zdraljevic, JP Roberts… - Nucleic acids …, 2017 - academic.oup.com
Studies in model organisms have yielded considerable insights into the etiology of disease
and our understanding of evolutionary processes. Caenorhabditis elegans is among the …

[图书][B] The evolution of sex determination

LW Beukeboom, N Perrin - 2014 - books.google.com
Sexual reproduction is a fundamental aspect of life. It is defined by the occurrence of meiosis
and the fusion of two gametes of different sexes or mating types. Sex-determination …

Evidence for dynamically organized modularity in the yeast protein–protein interaction network

JDJ Han, N Bertin, T Hao, DS Goldberg, GF Berriz… - Nature, 2004 - nature.com
In apparently scale-free protein–protein interaction networks, or 'interactome'networks,, most
proteins interact with few partners, whereas a small but significant proportion of proteins, the …

Numerous transitions of sex chromosomes in Diptera

B Vicoso, D Bachtrog - PLoS biology, 2015 - journals.plos.org
Many species groups, including mammals and many insects, determine sex using
heteromorphic sex chromosomes. Diptera flies, which include the model Drosophila …

The origin of new genes: glimpses from the young and old

M Long, E Betrán, K Thornton, W Wang - Nature Reviews Genetics, 2003 - nature.com
Genome data have revealed great variation in the numbers of genes in different organisms,
which indicates that there is a fundamental process of genome evolution: the origin of new …

A Map of the Interactome Network of the Metazoan C. elegans

S Li, CM Armstrong, N Bertin, H Ge, S Milstein… - Science, 2004 - science.org
To initiate studies on how protein-protein interaction (or “interactome”) networks relate to
multicellular functions, we have mapped a large fraction of the Caenorhabditis elegans …

Genetic and epigenetic mechanisms for gene expression and phenotypic variation in plant polyploids

ZJ Chen - Annu. Rev. Plant Biol., 2007 - annualreviews.org
Polyploidy, or whole-genome duplication (WGD), is an important genomic feature for all
eukaryotes, especially many plants and some animals. The common occurrence of …

Conservation, acquisition, and functional impact of sex-biased gene expression in mammals

S Naqvi, AK Godfrey, JF Hughes, ML Goodheart… - Science, 2019 - science.org
INTRODUCTION Sex differences are widespread in humans and other mammals. For
example, the distribution of height or body size is shifted upwards in males relative to …