[HTML][HTML] Sexual dimorphism in autoimmunity

K Rubtsova, P Marrack… - The Journal of clinical …, 2015 - Am Soc Clin Investig
Autoimmune diseases occur when the immune system attacks and destroys the organs and
tissues of its own host. Autoimmunity is the third most common type of disease in the United …

Role of mi R‐155 in the regulation of lymphocyte immune function and disease

N Seddiki, V Brezar, N Ruffin, Y Lévy… - …, 2014 - Wiley Online Library
Micro RNA s (mi RNA s) have emerged as critical regulators of gene expression within cells.
One particular mi RNA, mi R‐155, is highly expressed within lymphocytes (both B and T …

Circulating microRNAs as biomarkers for disease staging in multiple sclerosis

R Gandhi, B Healy, T Gholipour, S Egorova… - Annals of …, 2013 - Wiley Online Library
Objective MicroRNAs (miRNAs) are single‐stranded, small noncoding RNAs that regulate
gene expression. Because they are stable in serum, they are being developed as …

Dynamic chromatin regulatory landscape of human CAR T cell exhaustion

DG Gennert, RC Lynn, JM Granja… - Proceedings of the …, 2021 - National Acad Sciences
Dysfunction in T cells limits the efficacy of cancer immunotherapy. We profiled the
epigenome, transcriptome, and enhancer connectome of exhaustion-prone GD2-targeting …

Differential regulation of the Let-7 family of microRNAs in CD4+ T cells alters IL-10 expression

S Swaminathan, K Suzuki, N Seddiki… - The Journal of …, 2012 - journals.aai.org
Abstract MicroRNAs (miRNAs) are∼ 22-nt small RNAs that are important regulators of
mRNA turnover and translation. Recent studies have shown the importance of the miRNA …

Control of immunoregulatory molecules by miRNAs in T cell activation

A Rodríguez-Galán, L Fernández-Messina… - Frontiers in …, 2018 - frontiersin.org
MiRNA targeting of key immunoregulatory molecules fine-tunes the immune response. This
mechanism boosts or dampens immune functions to preserve homeostasis while supporting …

Signaling through purinergic receptors for ATP induces human cutaneous innate and adaptive Th17 responses: implications in the pathogenesis of psoriasis

ME Killeen, L Ferris, EA Kupetsky, L Falo… - The Journal of …, 2013 - journals.aai.org
Human cutaneous dendritic cells (DCs) have the ability to prime and bias Th17 lymphocytes.
However, the factors that stimulate cutaneous DCs to induce Th17 responses are not well …

MicroRNA regulation of T-lymphocyte immunity: modulation of molecular networks responsible for T-cell activation, differentiation, and development

K Podshivalova, DR Salomon - Critical Reviews™ in …, 2013 - dl.begellhouse.com
MicroRNAs (miRNA) are a class of small non-coding RNAs that constitute an essential and
evolutionarily conserved mechanism for post-transcriptional gene regulation. Multiple …

Sexual dimorphism of miRNA expression: a new perspective in understanding the sex bias of autoimmune diseases

R Dai, SA Ahmed - Therapeutics and clinical risk management, 2014 - Taylor & Francis
Autoimmune diseases encompass a diverse group of diseases which emanate from a
dysregulated immune system that launches a damaging attack on its own tissues …

[HTML][HTML] Myalgic encephalomyelitis or chronic fatigue syndrome: how could the illness develop?

G Morris, M Maes, M Berk, BK Puri - Metabolic brain disease, 2019 - Springer
A model of the development and progression of chronic fatigue syndrome (myalgic
encephalomyelitis), the aetiology of which is currently unknown, is put forward, starting with …