Interplay between SARS-CoV-2 and the type I interferon response
M Sa Ribero, N Jouvenet, M Dreux, S Nisole - PLoS pathogens, 2020 - journals.plos.org
The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is responsible for the
current COVID-19 pandemic. An unbalanced immune response, characterized by a weak …
current COVID-19 pandemic. An unbalanced immune response, characterized by a weak …
Lessons in self-defence: inhibition of virus entry by intrinsic immunity
S Majdoul, AA Compton - Nature Reviews Immunology, 2022 - nature.com
Virus entry, consisting of attachment to and penetration into the host target cell, is the first
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …
step of the virus life cycle and is a critical 'do or die'event that governs virus emergence in …
[HTML][HTML] Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses
Activation of unfolded protein responses (UPRs) in cancer cells undergoing endoplasmic
reticulum (ER) stress promotes survival. However, how UPR in tumor cells impacts anti …
reticulum (ER) stress promotes survival. However, how UPR in tumor cells impacts anti …
The emergence of Zika virus and its new clinical syndromes
TC Pierson, MS Diamond - Nature, 2018 - nature.com
Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …
threat because of its potential to generate explosive epidemics and ability to cause …
IFITM3 directly engages and shuttles incoming virus particles to lysosomes
Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) have emerged as important
innate immune effectors that prevent diverse virus infections in vertebrates. However, the …
innate immune effectors that prevent diverse virus infections in vertebrates. However, the …
[HTML][HTML] Three-dimensional human alveolar stem cell culture models reveal infection response to SARS-CoV-2
J Youk, T Kim, KV Evans, YI Jeong, Y Hur, SP Hong… - Cell Stem Cell, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is the cause of a
present pandemic, infects human lung alveolar type 2 (hAT2) cells. Characterizing …
present pandemic, infects human lung alveolar type 2 (hAT2) cells. Characterizing …
Viral-mediated activation and inhibition of programmed cell death
SG Verburg, RM Lelievre, MJ Westerveld… - PLoS …, 2022 - journals.plos.org
Viruses are ubiquitous intracellular genetic parasites that heavily rely on the infected cell to
complete their replication life cycle. This dependency on the host machinery forces viruses …
complete their replication life cycle. This dependency on the host machinery forces viruses …
Zika virus
S Masmejan, D Musso, M Vouga, L Pomar… - Pathogens, 2020 - mdpi.com
Zika virus (ZIKV), a neurotropic single-stranded RNA flavivirus, remains an important cause
of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations …
of congenital infection, fetal microcephaly, and Guillain-Barré syndrome in populations …
Guillain–Barré syndrome, transverse myelitis and infectious diseases
Guillain–Barré syndrome (GBS) and transverse myelitis (TM) both represent
immunologically mediated polyneuropathies of major clinical importance. Both are thought …
immunologically mediated polyneuropathies of major clinical importance. Both are thought …
Global interactomics uncovers extensive organellar targeting by Zika virus
E Coyaud, C Ranadheera, D Cheng… - Molecular & Cellular …, 2018 - ASBMB
Zika virus (ZIKV) is a membrane enveloped Flavivirus with a positive strand RNA genome,
transmitted by Aedes mosquitoes. The geographical range of ZIKV has dramatically …
transmitted by Aedes mosquitoes. The geographical range of ZIKV has dramatically …