Three-way junction skeleton biosensors based on aptamers, DNAzymes, and DNA hybridization probes

H Zahraee, Z Khoshbin, F Mohammadi… - TrAC Trends in …, 2023 - Elsevier
Nucleic acids can be used as building blocks for highly regular and complex structures at
the nanoscale due to their inherent self-assembly and programmability resulting from intra …

Multidimensional futuristic approaches to address the pandemics beyond COVID-19

SB Kotwal, N Orekondey, GP Saradadevi… - Heliyon, 2023 - cell.com
Globally, the impact of the coronavirus disease 2019 (COVID-19) pandemic has been
enormous and unrelenting with∼ 6.9 million deaths and∼ 765 million infections. This …

Intricate 3D architecture of a DNA mimic of GFP

LFM Passalacqua, MT Banco, JD Moon, X Li… - Nature, 2023 - nature.com
Numerous studies have shown how RNA molecules can adopt elaborate three-dimensional
(3D) architectures,–. By contrast, whether DNA can self-assemble into complex 3D folds …

In Situ Self‐Assembly of Fluorogenic RNA Nanozipper Enables Real‐Time Imaging of Single Viral mRNA Translation

YP Zhang, ZG Wang, YF Tian, LH Jiang… - Angewandte Chemie …, 2023 - Wiley Online Library
Real‐time visualization of individual viral mRNA translation activities in live cells is essential
to obtain critical details of viral mRNA dynamics and to detect its transient responses to …

Engineering of An Aptamer-Functionalized Fluorescent DNA Sensor for Cu (II) Responding in Living Tumor Cells

Y Mou, P Yin, M Chen, C Wei, Y Zhang… - Analytical …, 2023 - ACS Publications
Copper ions play vital roles in regulating life processes and being closely involved in
several diseases such as cancer. Although detection methods based on fluorescent sensors …

Construction of a novel fluorescent DNA aptasensor for the fast-response and sensitive detection of copper ions in industrial sewage

Y Mou, Y Zhang, X Lin, M Chen, Y Xia, S Zhu… - Analytical …, 2023 - pubs.rsc.org
Heavy metal pollution poses a great threat to the ecological environment and human health.
In particular, copper ions (Cu2+) play a vital role in regulating fundamental life behavior, and …

DNA-Aptamer-Based qPCR Using Light-Up Dyes for the Detection of Nucleic Acids

S Goyal, P Singh, S Sengupta, AB Muthukrishnan… - ACS …, 2023 - ACS Publications
Quantitative polymerase chain reaction (qPCR) is widely used in detection of nucleic acids,
but existing methods either lack sequence-specific detection or are costly because they use …

Viral aptamer screening and aptamer-based biosensors for virus detection: A review

C Hu, S Yang, S Li, X Liu, Y Liu, Z Chen, H Chen… - International Journal of …, 2024 - Elsevier
Virus-induced infectious diseases have a detrimental effect on public health and exert
significant influence on the global economy. Therefore, the rapid and accurate detection of …

A self-assembling split aptamer multiplex assay for SARS-COVID19 and miniaturization of a malachite green DNA-based aptamer

MR O'Steen, DM Kolpashchikov - Sensors and Actuators Reports, 2022 - Elsevier
Multiplex assays often rely on expensive sensors incorporating covalently linked fluorescent
dyes. Herein, we developed a self-assembling aptamer-based multiplex assay. This …

Int&in: A machine learning‐based web server for active split site identification in inteins

M Schmitz, JB Ballestin, J Liang, F Tomas… - Protein …, 2024 - Wiley Online Library
Inteins are proteins that excise themselves out of host proteins and ligate the flanking
polypeptides in an auto‐catalytic process called protein splicing. In nature, inteins are either …