IL-15 immunotherapy is a viable strategy for COVID-19

HK Kandikattu, SU Venkateshaiah, S Kumar… - Cytokine & growth factor …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a pulmonary inflammatory disease
induced by a newly recognized coronavirus, severe acute respiratory syndrome coronavirus …

Chronic pancreatitis and the development of pancreatic cancer

HK Kandikattu, SU Venkateshaiah… - Endocrine, Metabolic & …, 2020 - ingentaconnect.com
Pancreatitis is a fibro-inflammatory disorder of the pancreas that can occur acutely or
chronically as a result of the activation of digestive enzymes that damage pancreatic cells …

Sex hormones and lung inflammation

J Reyes-Garcia, LM Montano… - Lung Inflammation in …, 2021 - Springer
Inflammation is a characteristic marker in numerous lung disorders. Several immune cells,
such as macrophages, dendritic cells, eosinophils, as well as T and B lymphocytes …

[HTML][HTML] Update in interstitial lung disease 2019

SB Montesi, JH Fisher, FJ Martinez… - American journal of …, 2020 - atsjournals.org
The year 2019 brought advances in our understanding of pulmonary fibrosis, including
disease burden, elucidation of pathogenic drivers of fibrogenesis and potential therapeutic …

[HTML][HTML] IL-15 prevents renal fibrosis by inhibiting collagen synthesis: a new pathway in chronic kidney disease?

A Devocelle, L Lecru, S Ferlicot, T Bessede… - International Journal of …, 2021 - mdpi.com
Chronic kidney disease (CKD), secondary to renal fibrogenesis, is a public health burden.
The activation of interstitial myofibroblasts and excessive production of extracellular matrix …

[HTML][HTML] Monocytic myeloid-derived suppressor cells inhibit myofibroblastic differentiation in mesenchymal stem cells through IL-15 secretion

YC Cheuk, S Xu, D Zhu, Y Luo, T Chen… - Frontiers in Cell and …, 2022 - frontiersin.org
Background: Accumulating evidence indicates that mesenchymal stem cells (MSCs) are
precursors of myofibroblasts, which play a vital role in renal fibrosis. The close interaction …

Advanced signal processing and machine learning techniques for voltage sag causes detection in an electric power system

M Mishra, RR Panigrahi - International Transactions on …, 2020 - Wiley Online Library
In this manuscript, voltage sag causes (VSCs) detection in an electric power system is
studied using S‐transform (ST) and variational mode decomposition (VMD) techniques. The …

Overexpression of TIM-3 in macrophages aggravates pathogenesis of pulmonary fibrosis in mice

Y Wang, Q Kuai, F Gao, Y Wang, M He… - American journal of …, 2019 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive lung disorder and lacks effective
treatments because of unclear mechanisms. Aberrant function of alveolar macrophages is …

Theranostic nanoparticles for pancreatic cancer treatment

LR Jaidev, LS Chede… - Endocrine, Metabolic & …, 2021 - ingentaconnect.com
Pancreatic cancer is one of the low vascular permeable tumors with a high mortality rate.
The five-year survival period is∼ 5%. The field of drug delivery is at its pace in developing …

Profibrogenic role of IL-15 through IL-15 receptor alpha-mediated trans-presentation in the carbon tetrachloride-induced liver fibrosis model

M Cloutier, B Variya, SA Akbari, F Rexhepi… - Frontiers in …, 2024 - frontiersin.org
Background Inflammatory cytokines play key pathogenic roles in liver fibrosis. IL-15 is a
proinflammatory cytokine produced by myeloid cells. IL-15 promotes pathogenesis of …