Analytical Methods for Extraction and Identification of Primary and Secondary Metabolites of Apple (Malus domestica) Fruits: A Review

MA Acquavia, R Pascale, L Foti, G Carlucci, L Scrano… - Separations, 2021 - mdpi.com
Apples represent a greater proportion of the worldwide fruit supply, due to their availability
on the market and to the high number of existing cultivar varieties and apple-based products …

New insights into NF-κB signaling in innate immunity: focus on immunometabolic crosstalks

D Iacobazzi, P Convertini, S Todisco, A Santarsiero… - Biology, 2023 - mdpi.com
Simple Summary NF-κB transcription factors are leading modulators of innate immunity.
Recent investigations reveal their interplay with energetic metabolism as a central task of …

ACLY nuclear translocation in human macrophages drives proinflammatory gene expression by NF-κB acetylation

A Santarsiero, P Convertini, S Todisco, CL Pierri… - Cells, 2021 - mdpi.com
Macrophage stimulation by pathogen-associated molecular patterns (PAMPs) like
lipopolysaccharide (LPS) or lipoteichoic acid (LTA) drives a proinflammatory phenotype and …

The Phenolic Content of Pistacia lentiscus Leaf Extract and Its Antioxidant and Antidiabetic Properties

H Bouakline, S Bouknana, M Merzouki… - The Scientific World …, 2024 - Wiley Online Library
The aims of this study were to determine the polyphenolic profile, to estimate the total
phenolic and flavonoid contents, and to evaluate the antioxidant and antidiabetic activities of …

Predictive multi experiment approach for the determination of conjugated phenolic compounds in vegetal matrices by means of LC-MS/MS

E Oliva, F Fanti, S Palmieri, E Viteritti, F Eugelio… - Molecules, 2022 - mdpi.com
Polyphenols (PCs) are a numerous class of bioactive molecules and are known for their
antioxidant activity. In this work, the potential of the quadrupole/linear ion trap hybrid mass …

Targeted and semi-untargeted determination of phenolic compounds in plant matrices by high performance liquid chromatography-tandem mass spectrometry

E Oliva, E Viteritti, F Fanti, F Eugelio, A Pepe… - … of Chromatography A, 2021 - Elsevier
In this work two different acquisition approaches were used for the quantification and/or
tentative identification of phenolic compounds (PCs) in plant matrices by HPLC-MS/MS. A …

Redox Remodeling by Nutraceuticals for Prevention and Treatment of Acute and chronic inflammation

C Petrarca, D Viola - Antioxidants, 2023 - mdpi.com
Antioxidant-rich dietary regimens are considered the best practice to maintain health, control
inflammation, and prevent inflammatory diseases. Yet, nutraceuticals as food supplements …

ACLY as a modulator of liver cell functions and its role in Metabolic Dysfunction-Associated Steatohepatitis

P Convertini, A Santarsiero, S Todisco, M Gilio… - Journal of Translational …, 2023 - Springer
Abstract Background Non-alcoholic Fatty Liver Disease (NAFLD), now better known as
Metabolic (Dysfunction)-Associated Fatty Liver Disease (MAFLD) and its progression to …

Characterization of Quercetin Derivatives in Crossing Combination of Habanero White and Capsicum annuum Peppers and of Anti-Inflammatory and Cytotoxic …

MA Acquavia, R Pascale, I Pappalardo, A Santarsiero… - Separations, 2021 - mdpi.com
The overproduction of reactive oxygen species and the exposure of the human body to free
radicals contribute to the aetiology of many chronic health problems, such as cardiovascular …

Analysis of surfactants by mass spectrometry: Coming to grips with their diversity

R Pascale, MA Acquavia, A Onzo… - Mass Spectrometry …, 2023 - Wiley Online Library
Surfactants are surface‐active agents widely used in numerous applications in our daily
lives as personal care products, domestic, and industrial detergents. To determine complex …