The latest findings indicate the huge therapeutic potential of stem cells in regenerative
medicine, including the healing of chronic wounds. Main stem cell types involved in wound …

Cutaneous wound healing is a complex multiple phase process, which overlaps each other,
where several growth factors, cytokines, chemokines, and various cells interact in a well …

To meet the requirements for rapid tumor growth, a complex array of non-neoplastic cells are
recruited to the tumor microenvironment. These cells facilitate tumor development by …

Current pharmacotherapeutic options for treating obesity and related metabolic disorders
remain limited and ineffective. Emerging evidence shows that modulators of angiogenesis …

The vasculature plays an indispensible role in organ development and maintenance of
tissue homeostasis, such that disturbances to it impact greatly on developmental and …

Vascularization is among the top challenges that impede the clinical application of
engineered tissues. This challenge has spurred tremendous research endeavor, defined as …

The skin offers a perfect model system for studying the wound healing cascade, which
involves a finely tuned interplay between several cell types, pathways and processes. The …

Adipose tissue-derived stem cells (ADSC) are routinely isolated from the stromal vascular
fraction (SVF) of homogenized adipose tissue. Freshly isolated ADSC display surface …

The connection between obesity and accelerated cancer progression has been established,
but the mediating mechanisms are not well understood. We have shown that stromal cells …

Adult stem cells (ASCs) are tissue resident stem cells responsible for tissue homeostasis
and regeneration following injury. In uninjured tissues, ASCs exist in a nonproliferating …