Over the past decade, many studies have indicated that adolescence is a critical period of
brain development and maturation. The refinement and maturation of the central nervous …

Studies using animal models of adolescent exposure to alcohol, nicotine, cannabinoids, and
the stimulants cocaine, 3, 4-methylenedioxymethampethamine and methamphetamine have …

Supraphysiologic-dose anabolic-androgenic steroid (AAS) use is associated with
physiologic, cognitive, and brain abnormalities similar to those found in people at risk for …

Accumulating evidence from several studies has shown association between substance
use, dysregulation of the microbiome and psychiatric disorders such as depression, anxiety …

Cocaine addiction disorder is notably aggravated by concomitant cognitive and emotional
pathology that impedes recovery. We studied whether a persistent cognitive/emotional …

Aggressive behavior is not uniform, including proactive and reactive forms of aggression.
Aberrant functioning of the hypothalamic–pituitary–adrenal (HPA) axis is frequently …

Drug addiction is a devastating disorder with a huge economic and social burden for
modern society. Although an individual may slip into drug abuse throughout his/her life …

Drug addiction is a major public health concern in the United States costing taxpayers
billions in health care costs, lost productivity and law enforcement. However, the availability …

Social behaviour is disturbed in many substance abuse and psychiatric disorders. Given the
consensus that social behaviours of lower mammals may help to understand some human …

Objectives Individuals with a cocaine use disorder (CUD) are more likely to present anxiety,
which in turn negatively impacts substance use outcomes. Some evidence suggests that …