In today's research environment, a wealth of experimental/theoretical structural data is
available and the number of therapeutically relevant macromolecular structures is growing …

Plant resistance proteins (R proteins) recognize corresponding pathogen avirulence (Avr)
proteins either indirectly through detection of changes in their host protein targets or through …

The 1990s cultivated a generation of protein structure human predictors. As a result of
structural genomics and genome sequencing projects, and significant improvements in the …

Reports of human infection with Plasmodium knowlesi, a monkey malaria, suggest that it
and other nonhuman malaria species may be an emerging health problem. We report the …

We have identified a carboxylesterase produced in liquid cultures of the thermophilic
actinomycete Thermobifida fusca KW3 that were supplemented with poly (ethylene …

Ubiquitin (Ub) sorting receptors facilitate the targeting of ubiquitinated membrane proteins
into multivesicular bodies (MVBs). Ub-binding domains (UBDs) have been described in …

Apicomplexan parasites depend on the invasion of host cells for survival and proliferation.
Calcium-dependent signaling pathways appear to be essential for micronemal release and …

With each round of CASP (Critical Assessment of Techniques for Protein Structure
Prediction), automated prediction servers have played an increasingly important role. Today …

Bacterial genomes can evolve either by gene gain, gene loss, mutating existing genes,
and/or by duplication of existing genes. Recent studies have clearly demonstrated that the …

Background Multiple protein templates are commonly used in manual protein structure
prediction. However, few automated algorithms of selecting and combining multiple …