[HTML][HTML] The integral role of RNA in stress granule formation and function
D Campos-Melo, ZCE Hawley… - Frontiers in Cell and …, 2021 - frontiersin.org
Stress granules (SGs) are phase-separated, membraneless, cytoplasmic ribonucleoprotein
(RNP) assemblies whose primary function is to promote cell survival by condensing …
(RNP) assemblies whose primary function is to promote cell survival by condensing …
Tales of detailed poly (A) tails
AL Nicholson, AE Pasquinelli - Trends in cell biology, 2019 - cell.com
Poly (A) tails are non-templated additions of adenosines at the 3′ ends of most eukaryotic
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …
mRNAs. In the nucleus, these RNAs are co-transcriptionally cleaved at a poly (A) site and …
Nanopore native RNA sequencing of a human poly (A) transcriptome
High-throughput complementary DNA sequencing technologies have advanced our
understanding of transcriptome complexity and regulation. However, these methods lose …
understanding of transcriptome complexity and regulation. However, these methods lose …
An atlas of plant full-length RNA reveals tissue-specific and monocots–dicots conserved regulation of poly (A) tail length
Poly (A) tail is a hallmark of eukaryotic messenger RNA and its length plays an essential role
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
in regulating mRNA metabolism. However, a comprehensive resource for plant poly (A) tail …
Low RNA stability signifies increased post-transcriptional regulation of cell identity genes
Cell identity genes are distinct from other genes with respect to the epigenetic mechanisms
to activate their transcription, eg by super-enhancers and broad H3K4me3 domains …
to activate their transcription, eg by super-enhancers and broad H3K4me3 domains …
Measuring the tail: Methods for poly (A) tail profiling
A Brouze, PS Krawczyk… - Wiley Interdisciplinary …, 2023 - Wiley Online Library
Abstract The 3′‐end poly (A) tail is an important and potent feature of most mRNA
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …
molecules that affects mRNA fate and translation efficiency. Polyadenylation is a …
Drought induces epitranscriptome and proteome changes in stem-differentiating xylem of Populus trichocarpa
Y Gao, X Liu, Y Jin, J Wu, S Li, Y Li, B Chen… - Plant …, 2022 - academic.oup.com
Understanding gene expression and regulation requires insights into RNA transcription,
processing, modification, and translation. However, the relationship between the …
processing, modification, and translation. However, the relationship between the …
[HTML][HTML] Transcription dynamics regulate poly (A) tails and expression of the RNA degradation machinery to balance mRNA levels
Gene expression is regulated by the rates of synthesis and degradation of mRNAs, but how
these processes are coordinated is poorly understood. Here, we show that reduced …
these processes are coordinated is poorly understood. Here, we show that reduced …
tailfindr: alignment-free poly (A) length measurement for Oxford Nanopore RNA and DNA sequencing
Polyadenylation at the 3′-end is a major regulator of messenger RNA and its length is
known to affect nuclear export, stability, and translation, among others. Only recently have …
known to affect nuclear export, stability, and translation, among others. Only recently have …
Transcriptome-wide measurement of poly (A) tail length and composition at subnanogram total RNA sensitivity by PAIso-seq
Y Liu, Y Zhang, J Wang, F Lu - Nature Protocols, 2022 - nature.com
Poly (A) tails are added to the 3′ ends of most mRNAs in a non-templated manner and play
essential roles in post-transcriptional regulation, including mRNA export, stability and …
essential roles in post-transcriptional regulation, including mRNA export, stability and …