[HTML][HTML] Pathogenesis and multidisciplinary management of medication-related osteonecrosis of the jaw

L He, X Sun, Z Liu, Y Qiu, Y Niu - International journal of oral science, 2020 - nature.com
Medication-related osteonecrosis of the jaw (MRONJ) is a serious side effect of bone-
modifying agents and inhibits angiogenesis agents. Although the pathogenesis of MRONJ is …

Preclinical models of medication-related osteonecrosis of the jaw (MRONJ)

JI Aguirre, EJ Castillo, DB Kimmel - Bone, 2021 - Elsevier
Medication-related osteonecrosis of the jaw (MRONJ) is a potentially severe adverse event
affecting patients with cancer and patients with osteoporosis who have been treated with …

Current Understanding of the Pathophysiology of Osteonecrosis of the Jaw

J Chang, AE Hakam, LK McCauley - Current osteoporosis reports, 2018 - Springer
Abstract Purpose of Review Osteonecrosis of the jaw (ONJ) is a rare and severe necrotic
bone disease reflecting a compromise in the body's osseous healing mechanisms and …

Medication‐related osteonecrosis of the jaw: a literature review and update

S Kuroshima, FA Al‐Omari, M Sasaki, T Sawase - Genesis, 2022 - Wiley Online Library
Since the initial description of medication‐related osteonecrosis of the jaw (MRONJ) almost
two decades ago, the potential pathophysiology and risk factors have been elaborated on in …

Conservative surgical treatment of bisphosphonate‐related osteonecrosis of the jaw with Er, Cr: YSGG laser and platelet‐rich plasma: A longitudinal study

R Mauceri, V Panzarella, L Maniscalco… - BioMed research …, 2018 - Wiley Online Library
Introduction. The management of bisphosphonate‐related osteonecrosis of the jaw
(BRONJ), with no evidence‐based guidelines, remains controversial. We aimed to evaluate …

Pathophysiology of Medication‐Related Osteonecrosis of the Jaw—A Minireview

S Tetradis, MR Allen, SL Ruggiero - Journal of Bone and Mineral …, 2023 - academic.oup.com
Medication‐related osteonecrosis of the jaw (MRONJ) is a rare but serious adverse effect of
antiresorptive medications administered for control of osseous malignancy, osteoporosis, or …

Association between periodontitis and medication‐related osteonecrosis of the jaw: A systematic review and meta‐analysis

AI Lorenzo‐Pouso, M Pérez‐Sayáns… - Journal of Oral …, 2020 - Wiley Online Library
Consensus has yet to be reached about the prevention and treatment of medication‐related
osteonecrosis of the jaw (MRONJ), which is a treatment sequela of several antiresorptive …

Vasculature submucosal changes at early stages of osteonecrosis of the jaw (ONJ)

I Gkouveris, D Hadaya, A Soundia, O Bezouglaia… - Bone, 2019 - Elsevier
Osteonecrosis of the jaw (ONJ), a rare, but potentially severe side effect of anti-resorptive
medications, presents as exposed bone in the maxillofacial region lasting for at least 8 …

Rodents as an animal model for studying tooth extraction-related medication-related osteonecrosis of the jaw: assessment of outcomes

H Hadad, HR Matheus, SI Pai, FA Souza… - Archives of Oral …, 2023 - Elsevier
Objective To assess the outcomes of several rodent animal models for studying tooth
extraction-related medication-related osteonecrosis of the jaw (MRONJ). Design After a …

H‐type blood vessels participate in alveolar bone remodeling during murine tooth extraction healing

ZQ Yan, XK Wang, Y Zhou, ZG Wang, ZX Wang… - Oral …, 2020 - Wiley Online Library
Objectives We aimed to investigate whether skeletal‐specific H‐type blood vessels exist in
alveolar bone and how they function in alveolar bone remodeling. Materials and Methods H …