[HTML][HTML] Targeting NK cell inhibitory receptors for precision multiple myeloma immunotherapy
Innate immune surveillance of cancer involves multiple types of immune cells including the
innate lymphoid cells (ILCs). Natural killer (NK) cells are considered the most active ILC …
innate lymphoid cells (ILCs). Natural killer (NK) cells are considered the most active ILC …
[HTML][HTML] LAG-3 blockade with relatlimab (BMS-986016) restores anti-leukemic responses in chronic lymphocytic leukemia
C Sordo-Bahamonde, S Lorenzo-Herrero… - Cancers, 2021 - mdpi.com
Simple Summary Patients with chronic lymphocytic leukemia (CLL), the most frequent B cell
malignancy in western countries, develop a progressive immunosuppression, leading to …
malignancy in western countries, develop a progressive immunosuppression, leading to …
[HTML][HTML] PD-1 and LAG-3-positive T cells are associated with clinical outcomes of relapsed/refractory multiple myeloma patients
M Chen, J Zhu, X Yang, J Yao, Y Liu, Q Liu - European Journal of Medical …, 2022 - Springer
Objective To investigate the frequency of PD-1 and LAG-3-positive T cells in
relapsed/refractory multiple myeloma (RRMM) patients and its clinical significance. Methods …
relapsed/refractory multiple myeloma (RRMM) patients and its clinical significance. Methods …
The potentials of immune checkpoints for the treatment of blood malignancies
Immune checkpoints are the regulators of the immune system, which include stimulatory and
inhibitory receptors. They play substantial roles in the maintenance of immune system …
inhibitory receptors. They play substantial roles in the maintenance of immune system …