Exploring the pathogenesis of age-related macular degeneration: A review of the interplay between retinal pigment epithelium dysfunction and the innate immune …
JHC Wong, JYW Ma, AI Jobling, A Brandli… - Frontiers in …, 2022 - frontiersin.org
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss in the
older population. Classical hallmarks of early and intermediate AMD are accumulation of …
older population. Classical hallmarks of early and intermediate AMD are accumulation of …
Novel programmed cell death as therapeutic targets in age-related macular degeneration?
Age-related macular degeneration (AMD) is a leading cause of severe visual loss among
the elderly. AMD patients are tormented by progressive central blurring/loss of vision and …
the elderly. AMD patients are tormented by progressive central blurring/loss of vision and …
Acute central serous chorioretinopathy: factors influencing episode duration
A Daruich, A Matet, L Marchionno, JD De Azevedo… - Retina, 2017 - journals.lww.com
Purpose: To evaluate the influence of clinical and multimodal imaging parameters on the
duration of acute central serous chorioretinopathy (CSCR) episodes. Methods: Consecutive …
duration of acute central serous chorioretinopathy (CSCR) episodes. Methods: Consecutive …
Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity
S Datta, M Cano, G Satyanarayana, T Liu, L Wang… - Autophagy, 2023 - Taylor & Francis
Age-related macular degeneration (AMD), the leading cause of blindness among the
elderly, is without treatment for early disease. Degenerative retinal pigment epithelial (RPE) …
elderly, is without treatment for early disease. Degenerative retinal pigment epithelial (RPE) …
Metabolic features of mouse and human retinas: rods versus cones, macula versus periphery, retina versus RPE
Photoreceptors, especially cones, which are enriched in the human macula, have high
energy demands, making them vulnerable to metabolic stress. Metabolic dysfunction of …
energy demands, making them vulnerable to metabolic stress. Metabolic dysfunction of …
Deep learning predicts function of live retinal pigment epithelium from quantitative microscopy
Increases in the number of cell therapies in the preclinical and clinical phases have
prompted the need for reliable and noninvasive assays to validate transplant function in …
prompted the need for reliable and noninvasive assays to validate transplant function in …
Quantifying retinal pigment epithelium dysmorphia and loss of histologic autofluorescence in age-related macular degeneration
JA Gambril, KR Sloan, TA Swain… - … & visual science, 2019 - iovs.arvojournals.org
Purpose: Lipofuscin and melanolipofuscin organelles in retinal pigment epithelium (RPE)
cells are signal sources for clinical fundus autofluorescence (AF). To elucidate the …
cells are signal sources for clinical fundus autofluorescence (AF). To elucidate the …
[HTML][HTML] Electrohydrodynamic jet-printed ultrathin polycaprolactone scaffolds mimicking bruch's membrane for retinal pigment epithelial tissue engineering
Age-related macular degeneration (AMD) is the leading cause of visual loss and affects
millions of people worldwide. Dysfunction of the retinal pigment epithelium (RPE) is …
millions of people worldwide. Dysfunction of the retinal pigment epithelium (RPE) is …
Aging induces cell loss and a decline in phagosome processing in the mouse retinal pigment epithelium
JYW Ma, U Greferath, JHC Wong, LJ Fothergill… - Neurobiology of …, 2023 - Elsevier
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss and
dysfunction in the retinal pigment epithelium (RPE) with age is known to contribute to …
dysfunction in the retinal pigment epithelium (RPE) with age is known to contribute to …
[HTML][HTML] HSP90 acts as a senomorphic target in senescent retinal pigmental epithelial cells
DD Chen, X Peng, Y Wang, M Jiang, M Xue… - Aging (albany …, 2021 - ncbi.nlm.nih.gov
The senescence of retinal pigment epithelial (RPE) cells is associated with age-related
macular degeneration (AMD), a leading cause of blindness in the world. HSP90 is a …
macular degeneration (AMD), a leading cause of blindness in the world. HSP90 is a …