[HTML][HTML] Albendazole and mebendazole as anti-parasitic and anti-cancer agents: an update

JY Chai, BK Jung, SJ Hong - The Korean Journal of Parasitology, 2021 - ncbi.nlm.nih.gov
The use of albendazole and mebendazole, ie, benzimidazole broad-spectrum anthelmintics,
in treatment of parasitic infections, as well as cancers, is briefly reviewed. These drugs are …

Chitosan on the surface of nanoparticles for enhanced drug delivery: A comprehensive review

MH Elkomy, AA Ali, HM Eid - Journal of Controlled Release, 2022 - Elsevier
The ability of chitosan (CTS) to promote mucoadhesion, trigger positive/negative surface
interactions, and open tight junctions has inspired researchers to coat lipid-based and …

Advances and applications of chitosan-based nanomaterials as oral delivery carriers: A review

X Lang, T Wang, M Sun, X Chen, Y Liu - International journal of biological …, 2020 - Elsevier
The oral drug administration was convenient and comfortable route for patients.
Nevertheless, the oral uptake efficiency of many therapeutic agents was limited by …

Chitosan-coated nanostructured lipid carriers for transdermal delivery of tetrahydrocurcumin for breast cancer therapy

TH Truong, KP Alcantara, BPI Bulatao… - Carbohydrate …, 2022 - Elsevier
Chitosan (Ch)-coated nanostructured lipid carriers (NLCs) have great potential for
transdermal delivery with high localization of chemotherapeutics in breast cancer. This study …

Permeation enhancers loaded bilosomes for improved intestinal absorption and cytotoxic activity of doxorubicin

AA Sultan, GA Saad, GM El Maghraby - International Journal of …, 2023 - Elsevier
The clinical utility of doxorubicin is compromised due to dose related toxic side effects and
limited oral bioavailability with no oral formulation being marketed. Enhancement of …

Structure-based modifications of nano lipid carriers: Comparative review on release properties and anti-microbial activities of bioactive compounds

E Abedi, HR Akhavan, H Mohammadi, S Banasaz - Food Control, 2024 - Elsevier
The applications of solid lipid nanoparticles (SLN) and nanostructured lipid carrier (NLC)
might be reduced because of entrapment efficiency, rate of sustained drug release and drug …

Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Chemico-Biological …, 2022 - Elsevier
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …

Chitosan coated luteolin nanostructured lipid carriers: optimization, in vitro-ex vivo assessments and cytotoxicity study in breast cancer cells

SJ Gilani, M Bin-Jumah, M Rizwanullah, SS Imam… - Coatings, 2021 - mdpi.com
In the present study, luteolin (LTN)-encapsulated chitosan (CS) coated nanostructured lipid
carriers (NLCs) were formulated using the melt emulsification ultrasonication technique …

Chitosan-coated nanostructured lipid carriers for effective brain delivery of Tanshinone IIA in Parkinson's disease: interplay between nuclear factor-kappa β and …

DM Hassan, AH El-Kamel, EA Allam, BA Bakr… - Drug Delivery and …, 2024 - Springer
Parkinson's disease (PD) is the second most common progressive neurodegenerative
disorder associated with increased oxidative stress, the underlying vital process contributing …

Characterization of a novel pyruvate kinase from Trichinella spiralis and its participation in sugar metabolism, larval molting and development

WW Yue, SW Yan, R Zhang, YK Cheng… - PLoS Neglected …, 2022 - journals.plos.org
Background Pyruvate kinase widely exists in many parasites and plays an important role in
the energy production for the parasites. Pyruvate kinase might be a potential drug target for …