Prostate specific antigen (PSA) remains the most used biomarker in the management of
early prostate cancer (PCa), in spite of the problems related to false positive results and …

Abstract microRNAs (miRNAs) are small non-coding RNAs that control gene expression
posttranscriptionally and are part of the giant non codifying genoma. Cumulating data …

Radiotherapy is one of the most important treatment options for localized early-stage or
advanced-stage prostate cancer (CaP). Radioresistance (relapse after radiotherapy) is a …

Objective To test the expandability of active surveillance (AS) to Gleason score 3+ 4 cancers
by assessing the unfavorable disease risk in a large multi-institutional cohort. Materials and …

Prostate cancer (PCa) remains as one of the most controversial issues in health care
because of the dilemmas related to screening using Prostate Specific Antigen (PSA). A high …

Background Overtreatment is a well‐known clinical challenge in local prostate cancer (PCa).
Although risk assessment models have contributed to a better stratification of patients with …

Abstract Introduction: Prostate cancer (PCa) detection is accompanied by overdiagnosis and
mischaracterization of PCa. Therefore, new imaging modalities like shear wave …

Background To identify computer extracted in vivo dynamic contrast enhanced (DCE) MRI
markers associated with quantitative histomorphometric (QH) characteristics of microvessels …

Purpose: At our institution the eligibility criteria used to enroll patients in active surveillance
are clinical stage T1, prostate specific antigen density less than 0.15 ng/ml, biopsy Gleason …

Purpose We evaluated whether intraoperative frozen section analysis of the prostate surface
might provide significant information to ensure nerve sparing and minimize the positive …