Pancreas organogenesis: from bud to plexus to gland
FC Pan, C Wright - Developmental dynamics, 2011 - Wiley Online Library
Pancreas oganogenesis comprises a coordinated and highly complex interplay of signaling
events and transcriptional networks that guide a step‐wise process of organ development …
events and transcriptional networks that guide a step‐wise process of organ development …
The biliary tree—a reservoir of multipotent stem cells
V Cardinale, Y Wang, G Carpino, G Mendel… - Nature reviews …, 2012 - nature.com
The biliary tree is composed of intrahepatic and extrahepatic bile ducts, lined by mature
epithelial cells called cholangiocytes, and contains peribiliary glands deep within the duct …
epithelial cells called cholangiocytes, and contains peribiliary glands deep within the duct …
[PDF][PDF] Multipotent stem/progenitor cells in human biliary tree give rise to hepatocytes, cholangiocytes, and pancreatic islets
V Cardinale, Y Wang, G Carpino, CB Cui, M Gatto… - …, 2011 - Wiley Online Library
Multipotent stem/progenitors are present in peribiliary glands of extrahepatic biliary trees
from humans of all ages and in high numbers in hepato‐pancreatic common duct, cystic …
from humans of all ages and in high numbers in hepato‐pancreatic common duct, cystic …
Biliary tree stem/progenitor cells in glands of extrahepatic and intraheptic bile ducts: an anatomical in situ study yielding evidence of maturational lineages
Stem/progenitors have been identified intrahepatically in the canals of Hering and
extrahepatically in glands of the biliary tree. Glands of the biliary tree (peribiliary glands) are …
extrahepatically in glands of the biliary tree. Glands of the biliary tree (peribiliary glands) are …
Sox17 regulates organ lineage segregation of ventral foregut progenitor cells
JR Spence, AW Lange, SCJ Lin, KH Kaestner… - Developmental cell, 2009 - cell.com
The ventral pancreas, biliary system, and liver arise from the posterior ventral foregut, but the
cell-intrinsic pathway by which these organ lineages are separated is not known. Here we …
cell-intrinsic pathway by which these organ lineages are separated is not known. Here we …
In vivo reprogramming of Sox9+ cells in the liver to insulin-secreting ducts
A Banga, E Akinci, LV Greder… - Proceedings of the …, 2012 - National Acad Sciences
In embryonic development, the pancreas and liver share developmental history up to the
stage of bud formation. Therefore, we postulated that direct reprogramming of liver to …
stage of bud formation. Therefore, we postulated that direct reprogramming of liver to …
[PDF][PDF] Liver‐specific inactivation of Notch2, but not Notch1, compromises intrahepatic bile duct development in mice
F Geisler, F Nagl, PK Mazur, M Lee… - …, 2008 - Wiley Online Library
The Notch pathway is an evolutionary conserved, intercellular signaling pathway that plays
an important role in cell fate specification and the embryonic development of many organs …
an important role in cell fate specification and the embryonic development of many organs …
Hepatic FcRn regulates albumin homeostasis and susceptibility to liver injury
M Pyzik, T Rath, TT Kuo, S Win… - Proceedings of the …, 2017 - National Acad Sciences
The neonatal crystallizable fragment receptor (FcRn) is responsible for maintaining the long
half-life and high levels of the two most abundant circulating proteins, albumin and IgG. In …
half-life and high levels of the two most abundant circulating proteins, albumin and IgG. In …
[HTML][HTML] Cellular plasticity within the pancreas—lessons learned from development
S Puri, M Hebrok - Developmental cell, 2010 - cell.com
The pancreas has been the subject of intense research due to the debilitating diseases that
result from its dysfunction. In this review, we summarize current understanding of the critical …
result from its dysfunction. In this review, we summarize current understanding of the critical …
Biliary tree stem cells, precursors to pancreatic committed progenitors: evidence for possible life-long pancreatic organogenesis
Peribiliary glands (PBGs) in bile duct walls, and pancreatic duct glands (PDGs) associated
with pancreatic ducts, in humans of all ages, contain a continuous, ramifying network of cells …
with pancreatic ducts, in humans of all ages, contain a continuous, ramifying network of cells …