Advancements in molecular biology have led to a greater understanding of the individual
proteins responsible for generating cerebral edema. In large part, the study of cerebral …

Intracerebral hemorrhage (ICH) has one of the worst prognoses among patients with stroke.
Surgical measures have been adopted to relieve the mass effect of the hematoma, and …

Brain edema is a potentially fatal pathological state that occurs after brain injuries such as
stroke and head trauma. In the edematous brain, excess accumulation of extracellular fluid …

Introduction: Diabetes mellitus is a risk for brain injury. Brain injury is associated with acute
and chronic hyperglycaemia, insulin resistance, hyperinsulinemia, diabetic ketoacidosis …

Traumatic brain injury (TBI) is a complex and heterogeneous disorder with a tremendous
public health burden. It is grossly defined as an alteration in brain function or other evidence …

✓ Cerebral edema is caused by a variety of pathological conditions that affect the brain. It is
associated with two separate pathophysiological processes with distinct molecular and …

In the nervous system, the intracellular chloride concentration ([Cl−] i) determines the
strength and polarity of γ-aminobutyric acid (GABA)-mediated neurotransmission.[Cl−] i is …

Object Brain edema resulting from traumatic brain injury (TBI) or ischemia if uncontrolled
exhausts volume reserve and leads to raised intracranial pressure and brain herniation. The …

Neuronal chloride regulation is a determinant factor for the dynamic tuning of GABAergic
inhibition during and beyond brain development. This regulation is mainly dependent on the …

The brain achieves homeostasis of its intracellular and extracellular fluids by precisely
regulating the transport of solute and water across its major cellular barriers: endothelia of …