The biological activity mechanism of chlorogenic acid and its applications in food industry: A review

L Wang, X Pan, L Jiang, Y Chu, S Gao, X Jiang… - Frontiers in …, 2022 - frontiersin.org
Chlorogenic acid (CGA), also known as coffee tannic acid and 3-caffeoylquinic acid, is a
water-soluble polyphenolic phenylacrylate compound produced by plants through the …

A review of the protective effects of chlorogenic acid against different chemicals

R Rashidi, R Rezaee, A Shakeri… - Journal of Food …, 2022 - Wiley Online Library
Chlorogenic acid (CGA) is a naturally occurring non‐flavonoid polyphenol found in green
coffee beans, teas, certain fruits, and vegetables, that exerts antiviral, antitumor …

Anticancer plant-derivatives: Deciphering their oncopreventive and therapeutic potential in molecular terms

R Gahtori, AH Tripathi, A Kumari, N Negi… - Future Journal of …, 2023 - Springer
Background Over the years, phytomedicines have been widely used as natural modalities
for the treatment and prevention of various diseases by different ethnic groups across the …

Caffeic acid mitigates aflatoxin B1‐mediated toxicity in the male rat reproductive system by modulating inflammatory and apoptotic responses, testicular function, and …

SE Owumi, CE Irozuru, UO Arunsi… - Journal of food …, 2022 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is a toxic metabolite of public health concern. The present study
investigates the protective effects of caffeic acid (CA) against AFB1‐induced oxidative stress …

Omega-3 fatty acids abrogates oxido-inflammatory and mitochondrial dysfunction-associated apoptotic responses in testis of tamoxifen-treated rats

AF Odetayo, RE Akhigbe, MA Hamed… - Frontiers in …, 2024 - frontiersin.org
Background Tamoxifen (TAM) is a widely used drug in patients with gynecomastia and
breast cancer. TAM exerts its anticancer effects via its antiestrogenic activities. Unfortunately …

3-Indolepropionic acid upturned male reproductive function by reducing oxido-inflammatory responses and apoptosis along the hypothalamic-pituitary-gonadal axis of …

SE Owumi, MT Otunla, UO Arunsi, ES Najophe - Toxicology, 2021 - Elsevier
We examined the effect of 3-Indolepropionic acid (3-IPA), an antioxidant on the
organophosphorus pesticide chlorpyrifos (CPF)-induced reproductive toxicity in rats. The …

The protective effect of 3‐indolepropanoic acid on aflatoxin B1‐induced systemic perturbation of the liver and kidney function in rats

SE Owumi, UO Arunsi… - Fundamental & Clinical …, 2023 - Wiley Online Library
Abstract Aflatoxin B1 (AFB1) is known to derange the hepatorenal system by redox, DNA
adduct formation and apoptotic networks. Endogenous 3‐indole propionic acid (3‐IPA) is a …

Protective effect of Smilax excelsa L. pretreatment via antioxidant, anti‐inflammatory effects, and activation of Nrf‐2/HO‐1 pathway in testicular torsion model

M Cellat, CT İşler, A Uyar, M Kuzu… - Journal of food …, 2022 - Wiley Online Library
The protective effects of the ethanol extract of Smilax excelsa L.(SE) leaves were
investigated on testicular tissue of rats with a torsion model in this study. The chemical …

Chlorogenic acid alleviated testicular inflammation and apoptosis in tunicamycin induced endoplasmic reticulum stress

T Komeili–Movahhed, F Heidari… - Physiology …, 2023 - akjournals.com
Purpose Chlorogenic acid (CA) is a polyphenolic compound, found in many herbs and foods
including coffee, berries and potatoes. Anti-inflammatory, anti-oxidant, anti-cancer and anti …

Biochemical and histological alterations of doxorubicin‐induced neurotoxicity in rats: protective role of luteolin

IO Imosemi, SE Owumi… - Journal of Biochemical and …, 2022 - Wiley Online Library
Doxorubicin (DOX) is a chemotherapeutic drug used in the treatment of various cancer
types. DOX toxic side effects include neuronopathy and memory deficits. We investigated the …