Overview of microRNA biogenesis, mechanisms of actions, and circulation
MicroRNAs (miRNAs) are a class of non-coding RNAs that play important roles in regulating
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
gene expression. The majority of miRNAs are transcribed from DNA sequences into primary …
[HTML][HTML] Role of microRNAs in translation regulation and cancer
S Oliveto, M Mancino, N Manfrini… - World journal of biological …, 2017 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are pervasively expressed and regulate most biological functions.
They function by modulating transcriptional and translational programs and therefore they …
They function by modulating transcriptional and translational programs and therefore they …
Mechanisms of miRNA‐mediated gene regulation from common downregulation to mRNA‐specific upregulation
A Valinezhad Orang, R Safaralizadeh… - … journal of genomics, 2014 - Wiley Online Library
Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
regulatory gene families in eukaryotes. To date, 24521 microRNAs have been discovered …
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
Host dependency factors that are required for influenza A virus infection may serve as
therapeutic targets as the virus is less likely to bypass them under drug-mediated selection …
therapeutic targets as the virus is less likely to bypass them under drug-mediated selection …
Deregulated mitochondrial microRNAs in Alzheimer's disease: focus on synapse and mitochondria
Alzheimer's disease (AD) is the most common cause of dementia and is currently one of the
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …
biggest public health concerns in the world. Mitochondrial dysfunction in neurons is one of …
The role of microRNAs in inflammation
K Das, LVM Rao - International Journal of Molecular Sciences, 2022 - mdpi.com
Inflammation is a biological response of the immune system to various insults, such as
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …
pathogens, toxic compounds, damaged cells, and radiation. The complex network of pro …
Circulating microRNAs as biomarkers in cancer diagnosis
MMH Sohel - Life sciences, 2020 - Elsevier
MicroRNAs (miRNAs) are a group of tiny molecules of 18–22 nucleotide long noncoding
RNA that regulate the post-transcriptional gene expression through translational inhibition …
RNA that regulate the post-transcriptional gene expression through translational inhibition …
[HTML][HTML] RNA dysregulation in amyotrophic lateral sclerosis
Z Butti, SA Patten - Frontiers in genetics, 2019 - frontiersin.org
Amyotrophic lateral sclerosis (ALS) is the most common adult-onset motor neuron disease
and is characterized by the degeneration of upper and lower motor neurons. It has become …
and is characterized by the degeneration of upper and lower motor neurons. It has become …
Circulating miRNAs: cell–cell communication function?
A Turchinovich, TR Samatov, AG Tonevitsky… - Frontiers in …, 2013 - frontiersin.org
Nuclease resistant extracellular miRNAs have been found in all known biological fluids. The
biological function of extracellular miRNAs remains questionable; however, strong evidence …
biological function of extracellular miRNAs remains questionable; however, strong evidence …
MiRNAs: biology, biogenesis, their web-based tools, and databases
M Tafrihi, E Hasheminasab - Microrna, 2019 - ingentaconnect.com
Introduction: MicroRNAs (miRNAs), which are evolutionarily conserved, and endogenous
non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The …
non-coding RNAs, participate in the post-transcriptional regulation of eukaryotic genes. The …