[HTML][HTML] MicroRNAs: an update of applications in forensic science

A Rocchi, E Chiti, A Maiese, E Turillazzi, I Spinetti - Diagnostics, 2020 - mdpi.com
MicroRNAs (miRNAs) are a class of non-coding RNAs containing 18–24 nucleotides that
are involved in the regulation of many biochemical mechanisms in the human body. The …

Vitality and wound-age estimation in forensic pathology: review and future prospects

N Li, Q Du, R Bai, J Sun - Forensic sciences research, 2020 - academic.oup.com
Determining the age of a wound is challenging in forensic pathology, but it can contribute to
the reconstruction of crime scenes and lead to arrest of suspects. Forensic scholars have …

[HTML][HTML] Macrophage polarity and wound age determination

Y Kuninaka, Y Ishida, A Ishigami, M Nosaka… - Scientific Reports, 2022 - nature.com
We investigated the dynamics of the gene expression of M1 and M2 macrophage markers
during skin wound healing in mice. Expression of M1-macrophage markers, such as Il12a …

[HTML][HTML] MiRNAs as new tools in lesion vitality evaluation: a systematic review and their forensic applications

AC Manetti, A Maiese, A Baronti, E Mezzetti, P Frati… - Biomedicines, 2021 - mdpi.com
Wound vitality demonstration is one of the most challenging fields in forensic pathology. In
recent years, researchers focused on the application of histological and …

Histopathological, immunohistochemical, and molecular studies for determination of wound age and vitality in rats

AA Khalaf, EI Hassanen, AR Zaki… - International Wound …, 2019 - Wiley Online Library
In forensic medicine, it is vital to verify with the best attainable accuracy once injuries
occurred during vital or post‐mortem conditions. An immunohistochemical study was carried …

[HTML][HTML] A clue on the skin: a systematic review on immunohistochemical analyses of the ligature mark

G Mansueto, A Feola, P Zangani, A Porzio… - International Journal of …, 2022 - mdpi.com
Background: A ligature mark is a common injury in cases of hanging or strangulation.
Estimation of age and vitality of the ligature mark can be crucial for differentiating …

[HTML][HTML] Wound vitality in decomposed bodies: new frontiers through immunohistochemistry

G Bertozzi, M Ferrara, R La Russa, G Pollice… - Frontiers in …, 2021 - frontiersin.org
Background: The question about wound vitality and the estimation of wound age of
production are two of the classic investigation fields of forensic sciences. To answer this, the …

Assessing wound vitality in decomposed bodies: A review of the literature

G Vignali, L Franceschetti, GCL Attisano… - International Journal of …, 2023 - Springer
The capability of discriminating between a vital and a post-mortem injury has always been a
central theme in forensic pathology, particularly when the corpse is an advanced state of …

[HTML][HTML] Regulation of miRNAs as new tool for cutaneous vitality lesions demonstration in ligature marks in deaths by hanging

M Neri, M Fabbri, S D'Errico, M Di Paolo, P Frati… - Scientific Reports, 2019 - nature.com
This study aims to demonstrate that the application of miRNA expression in forensic
pathology, in cases of hanging, applying the method on skin samples. The proposed …

[HTML][HTML] State-of-the-art on wound vitality evaluation: a systematic review

A Maiese, AC Manetti, N Iacoponi, E Mezzetti… - International Journal of …, 2022 - mdpi.com
The vitality demonstration refers to determining if an injury has been caused ante-or post-
mortem, while wound age means to evaluate how long a subject has survived after the …