The benzophenone scaffold represents a ubiquitous structure in medicinal chemistry
because it is found in several naturally occurring molecules which exhibit a variety of …

The structural motif of coumarins is related with various biological activities and
pharmacological properties. Both natural coumarin extracted from various plants or a new …

Nanocrystalline bismuth vanadate has been steadily gaining attention in recent years due to
its potential energy conversion and eco-friendly nature. Herein, we report the green …

A sequence of coumarin analogs 5a–j was obtained by multi step synthesis from hydroxy
benzophenones (1a–j). The in vitro antiproliferative effect of the title compounds was tested …

This study was designed to determine the gastroprotective effect of a Mangifera indica leaf
decoction (AD), on different experimental models in rodents. The administration of AD up to …

The continuing threat to biodiversity lends urgency to the need of identification of
sustainable source of natural products. This is not so much trouble if there is a microbial …

Hypoxia is a feature of all solid tumours, contributing to tumour progression. Activation of HIF-
1α plays a critical role in promoting tumour angiogenesis and metastasis. Since its …

Background Hypoxic microenvironment is a common feature of solid tumors, which leads to
the promotion of cancer. The transcription factor, HIF-1α, expressed under hypoxic …

Hypoxia is an important module in all solid tumours to promote angiogenesis, invasion and
metastasis. Stabilization and subsequent nuclear localization of HIF-1α subunits result in the …

In the present investigation a series of novel 2-[1-(5-chloro-2-methoxy-phenyl)-5-methyl-1H-
pyrazol-4-yl]-5-(substituted-phenyl)-[1, 3, 4] oxadiazoles (4a–j) were synthesized by …