Phosphatidylserine (PS) is the major anionic phospholipid class particularly enriched in the
inner leaflet of the plasma membrane in neural tissues. PS is synthesized from …

The development of new techniques to study glial cells has revealed that they are active
participants in the development of functional neuronal circuits. Calcium imaging studies …

Alzheimer's disease (AD) is a severe neurodegenerative disorder still in search of effective
methods of diagnosis. Altered levels of the NMDA receptor co-agonist, d-serine, have been …

Assembly of synapses requires proper coordination between pre-and postsynaptic
elements. Identification of cellular and molecular events in synapse formation and …

Epilepsy is one of the most common neurological disorders characterized by recurrent
seizures. The mechanism of epilepsy remains unclear and previous studies suggest that N …

Amino acids are among the most important molecules in nature since they play central roles
both as building blocks of proteins and as intermediates in metabolism. The amino acid …

The glutamate neurotransmitter system is one of the major candidate pathways for the
pathophysiology of schizophrenia, and increased understanding of the pharmacology …

Shape-shifting, a phenomenon wide-spread in folklore, refers to the ability to physically
change from one identity to another, typically from an innocuous entity to a destructive one …

Rationale d-Serine is an endogenous co-agonist of the N-methyl-d-aspartate (NMDA)
receptor and has been suggested to improve cognitive deficits in schizophrenia. Objectives …

Aging is an inevitable process characterized by progressive loss of physiological integrity
and increased susceptibility to cancer, diabetes, cardiovascular, and neurodegenerative …