Patients with chronic granulomatous disease (CGD) suffer from recurrent, life-threatening
bacterial and fungal infections of the skin, the airways, the lymph nodes, liver, brain and …

Background Bacillus Calmette-Guérin (BCG) vaccine is a live attenuated bacterial vaccine
derived from Mycobacterium bovis, which is mostly administered to neonates in regions …

Background Chronic granulomatous disease (CGD) is a rare primary immunodeficiency
disorder of phagocytes resulting in impaired killing of bacteria and fungi. A mutation in one …

Chronic granulomatous Disease (CGD) is an immunodeficiency disorder affecting about 1 in
250,000 individuals. The disease is caused by mutations in the genes encoding the …

Neutrophils are particularly well known for their antimicrobial function. Although historically
they are regarded as strictly a phagocyte of the innate immune system, over time it has …

Primary immune deficiency (PID) disorders are clinically and molecularly heterogeneous
diseases. T cell receptor excision circles (TRECs) and κ (kappa)-deleting excision circles …

Many studies have explored differentially expressed genes (DEGs) between some
pathogens and hosts, but no study has focused on the interaction of DEGs between …

Chronic granulomatous Disease (CGD) is a rare innate immunodeficiency disorder caused
by mutations in one of the six genes (CYBA, CYBB, NCF1, NCF2, NCF4, and CYBC1/EROS) …

Turkey, with its population of some 75 million, has a high rate of consanguineous marriages.
Because the majority of the primary immunodeficiencies (PIDs) are inherited as autosomal …

CGD is more prevalent than initially believed with a birth prevalence of 1: 120 000. As
patients are increasingly diagnosed around the world and grow older, further manifestations …