Shortening and removal of the 3′ poly (A) tail of mature mRNA by poly (A)-specific 3′
exonucleases (deadenylases) is the initial and often rate-limiting step in mRNA degradation …

Eukaryotes possess a vast array of RNA-binding proteins (RBPs) that affect mRNAs in
diverse ways to control protein expression. Combinatorial regulation of mRNAs by RBPs is …

Collaboration among the multitude of RNA-binding proteins (RBPs) is ubiquitous, yet our
understanding of these key regulatory complexes has been limited to single RBPs. We …

RNA‐binding proteins (RBP s) play important roles for generating various cell types in many
developmental processes, including eggs and sperms. Nanos is widely known as an …

Nanos proteins repress the expression of target mRNA s by recruiting effector complexes
through non‐conserved N‐terminal regions. In vertebrates, Nanos proteins interact with the …

Nanos is expressed in multipotent cells, stem cells and primordial germ cells (PGCs) of
organisms as diverse as jellyfish and humans. It functions together with Pumilio to …

Oogenesis is a complex process regulated by precise coordination of multiple factors,
including maternal genes. Zygote arrest 1 (zar1) has been identified as an ovary-specific …

ABSTRACT PUF RNA-binding proteins have diverse roles in animal development, with a
broadly conserved role in stem cells. Two paradigmatic PUF proteins, FBF-1 and FBF-2 …

Despite the increasing understanding of female reproduction, the molecular diagnosis of
primary ovarian insufficiency (POI) is seldom obtained. The RNA‐binding protein NANOS3 …

The genetic mechanisms determining sex in teleost fishes are highly variable and the
master sex determining gene has only been identified in few species. Here we characterize …