Genetic causes and modifiers of autism spectrum disorder
L Rylaarsdam, A Guemez-Gamboa - Frontiers in cellular …, 2019 - frontiersin.org
Autism Spectrum Disorder (ASD) is one of the most prevalent neurodevelopmental
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …
disorders, affecting an estimated 1 in 59 children. ASD is highly genetically heterogeneous …
Sex differences in autism spectrum disorder: a review
Abstract Purpose of Review Neurodevelopmental disorders disproportionately affect males.
The mechanisms underlying male vulnerability or female protection are not known and …
The mechanisms underlying male vulnerability or female protection are not known and …
The neuropathology of autism: A systematic review of post-mortem studies of autism and related disorders
R Fetit, RF Hillary, DJ Price, SM Lawrie - Neuroscience & Biobehavioral …, 2021 - Elsevier
Post-mortem studies allow for the direct investigation of brain tissue in those with autism and
related disorders. Several review articles have focused on aspects of post-mortem …
related disorders. Several review articles have focused on aspects of post-mortem …
The role of sex-differential biology in risk for autism spectrum disorder
DM Werling - Biology of sex differences, 2016 - Springer
Autism spectrum disorder (ASD) is a developmental condition that affects approximately four
times as many males as females, a strong sex bias that has not yet been fully explained …
times as many males as females, a strong sex bias that has not yet been fully explained …
A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data
Genome-wide association studies (GWAS) have identified more than 100 schizophrenia
(SCZ)-associated loci, but using these findings to illuminate disease biology remains a …
(SCZ)-associated loci, but using these findings to illuminate disease biology remains a …
Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions
S Thongkorn, S Kanlayaprasit, P Panjabud, T Saeliw… - Scientific Reports, 2021 - nature.com
Our recent study has shown that prenatal exposure to bisphenol A (BPA) altered the
expression of genes associated with autism spectrum disorder (ASD). In this study, we …
expression of genes associated with autism spectrum disorder (ASD). In this study, we …
Developmental vitamin D deficiency and autism: putative pathogenic mechanisms
Autism is a neurodevelopmental disease that presents in early life. Despite a considerable
amount of studies, the neurobiological mechanisms underlying autism remain obscure. Both …
amount of studies, the neurobiological mechanisms underlying autism remain obscure. Both …
Aromatase in the human brain
I Azcoitia, P Mendez… - … : clinical research and …, 2021 - liebertpub.com
The aromatase cytochrome P450 (P450arom) enzyme, or estrogen synthase, which is
coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and …
coded by the CYP19A1 gene, is widely expressed in a subpopulation of excitatory and …
[HTML][HTML] Sex differences in antioxidant defence and the regulation of redox homeostasis in physiology and pathology
J Tiberi, V Cesarini, R Stefanelli, S Canterini… - Mechanisms of ageing …, 2023 - Elsevier
Reactive oxygen species (ROS) is a term that defines a group of unstable compounds
derived from exogenous sources or endogenous metabolism. Under physiological …
derived from exogenous sources or endogenous metabolism. Under physiological …
Sex differences in brain disorders
M Ziemka-Nalecz, P Pawelec, K Ziabska… - International Journal of …, 2023 - mdpi.com
A remarkable feature of the brain is its sexual dimorphism. Sexual dimorphism in brain
structure and function is associated with clinical implications documented previously in …
structure and function is associated with clinical implications documented previously in …