Highlights•ROS critically regulate the fate and function of stem cells from non-hematopoietic
and hematopoietic lineage to control bone hemostasis.•Excessive ROS accumulation in …

Lycopene is a type of carotenoid pigment widely distributed in various plants and fruits, with
tomatoes, carrots, and guava being the most abundant sources. Due to its high content of …

The excessive reactive oxygen species (ROS) is always associated with the degradation of
cartilage matrix during osteoarthritis (OA). The development of novel nanoenzymes with …

Osseointegration seems to be a foreign body reaction equilibrium due to the complicated
interactions between the immune and skeletal systems. The heterogeneity of the …

Osteoarthritis (OA) is a prevalent, chronic degenerative disease that affects people
worldwide. It is characterized by the destruction of cartilage and inflammatory reactions …

Background Osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs)
is an essential event in alveolar bone regeneration. Oxidative stress may be the main …

Periodontitis comprises a series of inflammatory responses resulting in alveolar bone loss.
The suppression of osteogenesis of periodontal ligament stem cells (PDLSCs) by …

An imbalance of antioxidants and free radicals in the body delays the wound healing
process. Ideal acute and chronic wound dressing materials require significant antioxidant …

Background Cardiac fibrosis is the most important pathogenesis leading to cardiac
remodeling and heart failure after myocardial infarction (MI). Tissue nonspecific alkaline …

Background Human periodontal ligament stem cells (hPDLSCs) are ideal seed cells for
periodontal regeneration. A greater understanding of the dynamic protein profiles during …