Small-angle X-ray and neutron scattering

CM Jeffries, J Ilavsky, A Martel, S Hinrichs… - Nature Reviews …, 2021 - nature.com
Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …

The MRE11–RAD50–NBS1 complex conducts the orchestration of damage signaling and outcomes to stress in DNA replication and repair

A Syed, JA Tainer - Annual review of biochemistry, 2018 - annualreviews.org
Genomic instability in disease and its fidelity in health depend on the DNA damage
response (DDR), regulated in part from the complex of meiotic recombination 11 homolog 1 …

Accurate design of megadalton-scale two-component icosahedral protein complexes

JB Bale, S Gonen, Y Liu, W Sheffler, D Ellis, C Thomas… - Science, 2016 - science.org
Nature provides many examples of self-and co-assembling protein-based molecular
machines, including icosahedral protein cages that serve as scaffolds, enzymes, and …

[HTML][HTML] A practical guide to small angle X-ray scattering (SAXS) of flexible and intrinsically disordered proteins

AG Kikhney, DI Svergun - FEBS letters, 2015 - Elsevier
Small-angle X-ray scattering (SAXS) is a biophysical method to study the overall shape and
structural transitions of biological macromolecules in solution. SAXS provides low resolution …

FoXS, FoXSDock and MultiFoXS: Single-state and multi-state structural modeling of proteins and their complexes based on SAXS profiles

D Schneidman-Duhovny, M Hammel… - Nucleic acids …, 2016 - academic.oup.com
Abstract Small Angle X-ray Scattering (SAXS) is an increasingly common and useful
technique for structural characterization of molecules in solution. A SAXS experiment …

Block copolymer–based porous carbon fibers

Z Zhou, T Liu, AU Khan, G Liu - Science advances, 2019 - science.org
Carbon fibers have high surface areas and rich functionalities for interacting with ions,
molecules, and particles. However, the control over their porosity remains challenging …

[PDF][PDF] New developments in the ATSAS program package for small-angle scattering data analysis

MV Petoukhov, D Franke, AV Shkumatov… - Journal of applied …, 2012 - journals.iucr.org
New developments in the program package ATSAS (version 2.4) for the processing and
analysis of isotropic small-angle X-ray and neutron scattering data are described. They …

Accurate assessment of mass, models and resolution by small-angle scattering

RP Rambo, JA Tainer - Nature, 2013 - nature.com
Modern small-angle scattering (SAS) experiments with X-rays or neutrons provide a
comprehensive, resolution-limited observation of the thermodynamic state. However …

Design of biologically active binary protein 2D materials

AJ Ben-Sasson, JL Watson, W Sheffler, MC Johnson… - Nature, 2021 - nature.com
Ordered two-dimensional arrays such as S-layers, and designed analogues,–have intrigued
bioengineers,, but with the exception of a single lattice formed with flexible linkers, they are …

Accurate SAXS profile computation and its assessment by contrast variation experiments

D Schneidman-Duhovny, M Hammel, JA Tainer… - Biophysical journal, 2013 - cell.com
A major challenge in structural biology is to characterize structures of proteins and their
assemblies in solution. At low resolution, such a characterization may be achieved by small …