[HTML][HTML] Impact of common ALDH2 inactivating mutation and alcohol consumption on Alzheimer's disease

T Seike, CH Chen, D Mochly-Rosen - Frontiers in Aging Neuroscience, 2023 - frontiersin.org
Aldehyde dehydrogenase 2 (ALDH2) is an enzyme found in the mitochondrial matrix that
plays a central role in alcohol and aldehyde metabolism. A common ALDH2 polymorphism …

[HTML][HTML] Targeting mitochondrial quality control of T cells: Regulating the immune response in HCC

Y Xia, B Gao, X Zhang - Frontiers in Oncology, 2022 - frontiersin.org
Most of the primary hepatocellular carcinoma (HCC) develops from Viral Hepatitis including
Hepatitis B virus, Hepatitis C Virus, and Nonalcoholic Steatohepatitis. Herein, T cells play …

Diabetes Driven Oncogenesis and Anticancer Potential of Repurposed Antidiabetic Drug: A Systemic Review

I Khan, A Kamal, S Akhtar - Cell Biochemistry and Biophysics, 2024 - Springer
Diabetes and cancer are two prevalent disorders, pose significant public health challenges
and contribute substantially to global mortality rates, with solely 10 million reported cancer …

[HTML][HTML] The immune response as a therapeutic target in non-alcoholic fatty liver disease

N Ortiz-Lopez, C Fuenzalida, MS Dufeu… - Frontiers in …, 2022 - frontiersin.org
Non-alcoholic fatty liver disease (NAFLD) is a complex and heterogeneous disorder
considered a liver-damaging manifestation of metabolic syndrome. Its prevalence has …

Immune cell profile and immune‐related gene expression of obese peripheral blood and liver tissue

JM Taylor, A Li, CS McLachlan - FEBS letters, 2022 - Wiley Online Library
Obesity is associated with changes in immune cell subpopulations. However, tissue and
blood obesity‐responsive immune phenotypic pathways have not been contrasted. Here …

[PDF][PDF] Correlation between regulatory T cells and autologous serum skin test among chronic spontaneous urticaria patients

A Mohamed, S Taha, A Ahmed, M Atwa - Egypt J Immunol, 2022 - ejimmunology.org
Chronic spontaneous urticaria (CSU) is considered as an autoimmune disorder in around
30-50% of cases and referred to as chronic autoimmune urticaria. T regulatory cells (Tregs) …