Characterizing hepatocellular carcinoma stem markers and their corresponding susceptibility to NK-cell based immunotherapy
Introduction Hepatocellular carcinoma (HCC) is the most common primary liver cancer and
is the fourth-leading cause of all cancer-related deaths around the world. Liver …
is the fourth-leading cause of all cancer-related deaths around the world. Liver …
Natural killer cells for pancreatic cancer immunotherapy: Role of nanoparticles
Advanced pancreatic cancer patients have a dismal prognosis despite advances in
integrative therapy. The field of tumor immunology has witnessed significant advancements …
integrative therapy. The field of tumor immunology has witnessed significant advancements …
Osteoclasts and probiotics mediate significant expansion, functional activation and supercharging in NK, γδ T, and CD3+ T cells: use in cancer immunotherapy
Our previous studies have introduced osteoclasts (OCs) as major activators of NK cells. It
was found that OCs exhibit the capabilities of inducing cell expansion as well as increasing …
was found that OCs exhibit the capabilities of inducing cell expansion as well as increasing …
Exploring the Potential of Natural Killer Cell-Based Immunotherapy in Targeting High-Grade Serous Ovarian Carcinomas
High-grade serous ovarian cancers (HGSOCs) likely consist of poorly differentiated stem-
like cells (PDSLCs) and differentiated tumor cells. Conventional therapeutics are incapable …
like cells (PDSLCs) and differentiated tumor cells. Conventional therapeutics are incapable …
Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro
Despite advancements in the field of cancer therapeutics, the five-year survival rate remains
low in oral cancer patients. Therefore, the effective therapeutics are needed against oral …
low in oral cancer patients. Therefore, the effective therapeutics are needed against oral …
Supercharged NK Cell-Based Immuotherapy in Humanized Bone Marrow Liver and Thymus (Hu-BLT) Mice Model of Oral, Pancreatic, Glioblastoma, Hepatic …
In this paper, we review a number of in vitro and in vivo studies regarding the efficacy of
supercharged NK (sNK) cell therapy in elimination or treatment of cancer. We have …
supercharged NK (sNK) cell therapy in elimination or treatment of cancer. We have …
The interplay between natural killer cells and pancreatic stellate cells in pancreatic ductal adenocarcinoma
R Fincham - 2024 - qmro.qmul.ac.uk
Pancreatic ductal adenocarcinoma (PDAC) is a disease with dismal prognosis. With five-
year survival rates of less than 11%, PDAC is set to become the second leading cause of …
year survival rates of less than 11%, PDAC is set to become the second leading cause of …
Commentary: Ovarian cancer; path to effective treatments
Despite advancements in cancer therapeutics such as checkpoint inhibitors and some
targeted therapies, we have not achieved success in effectively treating ovarian cancer …
targeted therapies, we have not achieved success in effectively treating ovarian cancer …
Oral Cancer: Past, present and future of NK cell-based cancer immunotherapy
Despite advancements in the field of cancer therapeutics the five-year survival rate remains
low in oral cancer patients. There, the effective therapeutics are needed to control the …
low in oral cancer patients. There, the effective therapeutics are needed to control the …
Supercharged NK cells, unlike primary activated NK cells, effectively target ovarian cancer cells irrespective of MHC-class I expression
Ovarian cancers are the fifth leading cause of cancer-related death among women in the
United States. Significant decreases in the numbers and function of NK-cells in patients, as …
United States. Significant decreases in the numbers and function of NK-cells in patients, as …