Highlights What are the main findings? Mucus, as the most widely distributed biofilm and
vital protective barrier on the surface of mucous membranes throughout the body, fulfills a …

Acquired resistance to oxaliplatin is considered as the primary reason for failure in colorectal
cancer (CRC) therapy. Identifying the underlying resistance mechanisms may improve CRC …

Fluorouracil (5-FU) is a chemotherapy drug used to treat tumors. Previous studies have
shown that Akkermansia muciniphila (A. muciniphila) and its outer membrane protein …

Agonist-mediated stimulated pathway of mucin and insulin release are biphasic in which
rapid fusion of pre-docked granules is followed by slow docking and fusion of granules from …

Mucinous colorectal adenocarcinoma (MCAC) is a distinct subtype of colorectal carcinoma
(CRC). The prognostic and predictive significance of mucinous histology remains …

Agonist-mediated stimulated pathway of mucin and insulin release is biphasic in which a
rapid fusion of pre-docked granules is followed by slow docking and fusion of granules from …

Mucinous carcinomas are tumors with poor prognosis and secrete a large amount of mucus.
The development of an in vitro model that reconstitutes the mucin-rich microenvironment of …