The glial cell of the peripheral nervous system (PNS), the Schwann cell (SC), counts among
the most multifaceted cells of the body. During development, SCs secure neuronal survival …

Significant progress has been made in the treatment of spinal cord injury (SCI). Advances in
post-trauma management and intensive rehabilitation have significantly improved the …

Axonal regeneration in the central nervous system (CNS) is a highly energy-demanding
process. Extrinsic insults and intrinsic restrictions lead to an energy crisis in injured axons …

Spinal cord injury (SCI) causes motor, sensory and automatic impairment due to rarely axon
regeneration. Developing effective treatment for SCI in the clinic is extremely challenging …

Spinal cord injury (SCI) is a devastating injury that causes permanent loss of sensation and
motor function. SCI repair is a significant challenge due to the limited regenerating ability of …

Abstract An implanted neurotrophin-3 (NT3)-chitosan scaffold can recruit endogenous
neural stem cells to migrate to a lesion region and differentiate into mature neurons after …

Spinal cord injury (SCI) often results in life-long sensorimotor impairment. Spontaneous
recovery from SCI is limited, as supraspinal fibers cannot spontaneously regenerate to form …

Propriospinal interneurons (INs) communicate information over short and long distances
within the spinal cord. They act to coordinate different parts of the body by linking motor …

Locomotor function, mediated by lumbar neural circuitry, is modulated by descending spinal
pathways. Spinal cord injury (SCI) interrupts descending projections and denervates lumbar …

Introduction Spinal cord injury (SCI) affects 25,000–50,000 people around the world each
year and there is no cure for SCI patients currently. The primary injury damages spinal cord …