Cancer stem cells—origins and biomarkers: perspectives for targeted personalized therapies
L Walcher, AK Kistenmacher, H Suo, R Kitte… - Frontiers in …, 2020 - frontiersin.org
The use of biomarkers in diagnosis, therapy and prognosis has gained increasing interest
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
over the last decades. In particular, the analysis of biomarkers in cancer patients within the …
Multidrug resistance in cancer: understanding molecular mechanisms, immunoprevention and therapeutic approaches
Cancer is one of the leading causes of death worldwide. Several treatments are available for
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
cancer treatment, but many treatment methods are ineffective against multidrug-resistant …
Lung cancers: molecular characterization, clonal heterogeneity and evolution, and cancer stem cells
U Testa, G Castelli, E Pelosi - Cancers, 2018 - mdpi.com
Lung cancer causes the largest number of cancer-related deaths in the world. Most (85%) of
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …
lung cancers are classified as non-small-cell lung cancer (NSCLC) and small-cell lung …
A DNA hypomethylation signature predicts antitumor activity of LSD1 inhibitors in SCLC
HP Mohammad, KN Smitheman, CD Kamat, D Soong… - Cancer cell, 2015 - cell.com
Epigenetic dysregulation has emerged as an important mechanism in cancer. Alterations in
epigenetic machinery have become a major focus for targeted therapies. The current report …
epigenetic machinery have become a major focus for targeted therapies. The current report …
Multi-drug resistance in cancer chemotherapeutics: mechanisms and lab approaches
Q Wu, Z Yang, Y Nie, Y Shi, D Fan - Cancer letters, 2014 - Elsevier
Multi-drug resistance (MDR) has become the largest obstacle to the success of cancer
chemotherapies. The mechanisms of MDR and the approaches to test MDR have been …
chemotherapies. The mechanisms of MDR and the approaches to test MDR have been …
New insights into small‐cell lung cancer development and therapy
Y Wang, S Zou, Z Zhao, P Liu, C Ke… - Cell Biology …, 2020 - Wiley Online Library
Small‐cell lung cancer (SCLC) accounts for approximately 15% of lung cancer cases;
however, it is characterized by easy relapse and low survival rate, leading to one of the most …
however, it is characterized by easy relapse and low survival rate, leading to one of the most …
[HTML][HTML] The role of stem cells in small-cell lung cancer: evidence from chemoresistance to immunotherapy
W Guo, T Qiao, T Li - Seminars in Cancer Biology, 2022 - Elsevier
Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer, accounting for
approximately 15% among all lung cancers. Despite the ability of chemotherapy, the first …
approximately 15% among all lung cancers. Despite the ability of chemotherapy, the first …
Cancer stem cells in drug resistant lung cancer: Targeting cell surface markers and signaling pathways
Lung cancer is the leading cause of cancer mortality worldwide. Despite advances in anti-
cancer therapies such as chemotherapy, radiotherapy and targeted therapies, five-year …
cancer therapies such as chemotherapy, radiotherapy and targeted therapies, five-year …
(−)-Epigallocatechin Gallate (EGCG) enhances the sensitivity of colorectal cancer cells to 5-FU by inhibiting GRP78/NF-κB/miR-155-5p/MDR1 pathway
X La, L Zhang, Z Li, H Li, Y Yang - Journal of agricultural and food …, 2019 - ACS Publications
Green tea accounts for approximately 20% of the world's total tea yield.(−)-Epigallocatechin
gallate (EGCG) is an active catechin in green tea, which suppresses tumor growth and …
gallate (EGCG) is an active catechin in green tea, which suppresses tumor growth and …
Small cell lung cancer screen of oncology drugs, investigational agents, and gene and microRNA expression
E Polley, M Kunkel, D Evans, T Silvers… - Journal of the …, 2016 - academic.oup.com
Background: Small cell lung carcinoma (SCLC) is an aggressive, recalcitrant cancer, often
metastatic at diagnosis and unresponsive to chemotherapy upon recurrence, thus it is …
metastatic at diagnosis and unresponsive to chemotherapy upon recurrence, thus it is …