MicroRNAs (miRNAs) are short, regulatory RNAs that act as post-transcriptional repressors
of gene expression in diverse biological contexts. The emergence of small RNA-mediated …

MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …

Argonaute (AGO) proteins associate with small RNAs to direct their effector function on
complementary transcripts. The nematode Caenorhabditis elegans contains an expanded …

Small RNAs of 20–30 nucleotides can target both chromatin and transcripts, and thereby
keep both the genome and the transcriptome under extensive surveillance. Recent progress …

Small RNAs directly or indirectly impact nearly every biological process in eukaryotic cells.
To perform their myriad roles, not only must precise small RNA species be generated, but …

During the past decade, small non-coding RNAs have rapidly emerged as important
contributors to gene regulation. To carry out their biological functions, these small RNAs …

Argonaute (AGO) proteins recruit small RNAs to form the core of RNAi effector complexes.
Arabidopsis encodes ten AGO proteins and a large network of small RNAs. How these small …

It is well established that 20-to 30-nt small RNAs, including small interfering RNAs,
microRNAs and Piwi-interacting RNAs, play crucial roles in regulating gene expression and …

The shoot apical meristem (SAM) comprises a group of undifferentiated cells that divide to
maintain the plant meristem and also give rise to all shoot organs. SAM fate is specified by …

RNA interference (RNAi) is a natural process through which expression of a targeted gene
can be knocked down with high specificity and selectivity. Using available technology and …