Osteoporosis and periodontal diseases–An update on their association and mechanistic links

B Yu, CY Wang - Periodontology 2000, 2022 - Wiley Online Library
Periodontitis and osteoporosis are prevalent inflammation‐associated skeletal disorders that
pose significant public health challenges to our aging population. Both periodontitis and …

Glucocorticoid-induced osteoporosis: an update

J Compston - Endocrine, 2018 - Springer
Glucocorticoid-induced osteoporosis is the most common secondary cause of osteoporosis
and the resulting fractures cause significant morbidity. Following initiation of oral …

Staphylococcal osteomyelitis: disease progression, treatment challenges, and future directions

N Kavanagh, EJ Ryan, A Widaa, G Sexton… - Clinical microbiology …, 2018 - Am Soc Microbiol
Osteomyelitis is an inflammatory bone disease that is caused by an infecting microorganism
and leads to progressive bone destruction and loss. The most common causative species …

Physiological bone remodeling: systemic regulation and growth factor involvement

JA Siddiqui, NC Partridge - Physiology, 2016 - journals.physiology.org
Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone
formation and resorption. The balance between the two phases is crucial for sustaining bone …

Parathyroid hormone directs bone marrow mesenchymal cell fate

Y Fan, J Hanai, PT Le, R Bi, D Maridas, V DeMambro… - Cell metabolism, 2017 - cell.com
Intermittent PTH administration builds bone mass and prevents fractures, but its mechanism
of action is unclear. We genetically deleted the PTH/PTHrP receptor (PTH1R) in …

Endocrine role of bone in the regulation of energy metabolism

R Zhou, Q Guo, Y Xiao, Q Guo, Y Huang, C Li, X Luo - Bone research, 2021 - nature.com
Abstracts Bone mainly functions as a supportive framework for the whole body and is the
major regulator of calcium homeostasis and hematopoietic function. Recently, an increasing …

[HTML][HTML] Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis …

SC Tao, T Yuan, BY Rui, ZZ Zhu, SC Guo… - Theranostics, 2017 - ncbi.nlm.nih.gov
An excess of glucocorticoids (GCs) is reported to be one of the most common causes of
osteonecrosis of the femoral head (ONFH). In addition, GCs can induce bone cell apoptosis …

Osteocyte-driven bone remodeling

T Bellido - Calcified tissue international, 2014 - Springer
Osteocytes, the most abundant cells in bone, have been long postulated to detect and
respond to mechanical and hormonal stimuli and to coordinate the function of osteoblasts …

Glucocorticoids and bone: consequences of endogenous and exogenous excess and replacement therapy

RS Hardy, H Zhou, MJ Seibel, MS Cooper - Endocrine reviews, 2018 - academic.oup.com
Osteoporosis associated with long-term glucocorticoid therapy remains a common and
serious bone disease. Additionally, in recent years it has become clear that more subtle …

Glucocorticoid‐induced bone disease

RS Weinstein - Primer on the metabolic bone diseases and …, 2013 - Wiley Online Library
Glucocorticoid‐induced osteoporosis (GIO) is the second most common form of osteoporosis
and is the most common iatrogenic form of the disease. Fractures may occur in 30% to 50 …